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科研机构
上海药物研究所 [538]
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期刊论文 [532]
会议论文 [4]
学位论文 [2]
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2021 [37]
2020 [33]
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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
The regulatory role of MiR-203 in oxidative stress induced cell injury through the CBS/H2S pathway
期刊论文
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2022, 卷号: 118, 页码: 31-38
作者:
Zhang, Qiuyan
;
Shen, Zhuqing
;
Shen, Yaqi
;
Ma, Muye
;
Jue, Hao
收藏
  |  
浏览/下载:220/0
  |  
提交时间:2022/01/04
Cerebral infarction
Cystathionine-beta-synthase
miRNA-203
Hydrogen sulfide
A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256
作者:
Dong, Lei
;
Zhang, Min-Yu
;
Han, Hai-Hao
;
Zang, Yi
;
Chen, Guo-Rong
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  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
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  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:
Yin, Jianpeng
;
Zhan, Desheng
;
Ma, Hui
;
Liu, Huanan
;
Yu, Lifang
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  |  
浏览/下载:34/0
  |  
提交时间:2021/12/16
YLF466D
AMPK activator
glucose metabolism
lipid metabolism
MIRI
domino reaction
C-H activation
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
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  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
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  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson
期刊论文
FITOTERAPIA, 2021, 卷号: 154, 页码: 5
作者:
Wang, Ai-Zhu
;
Fang, Qiang-Qiang
;
Feng, Tong-Tong
;
Wei, Ren-Jie
;
Jiang, Kun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/12/01
Hypericum acmosepalum
Clusiaceae
Xanthones
Antioxidant
Cytotoxicity
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/01
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
期刊论文
CELL RESEARCH, 2021, 页码: 18
作者:
Xu, Xiang
;
Ding, Guangjin
;
Liu, Caizhi
;
Ding, Yuhan
;
Chen, Xiaoxin
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
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