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上海药物研究所 [38]
复旦大学上海医学院 [9]
大连化学物理研究所 [8]
湖南大学 [7]
四川大学 [6]
安徽大学 [5]
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期刊论文 [116]
学位论文 [1]
发表日期
2018 [117]
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Biology [1]
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Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2018
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhao, Jihui
;
Deng, Pan
;
Zheng, Mingyue
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
A Biomimetic Human Gut-on-a-Chip for Modeling Drug Metabolism in Intestine
期刊论文
ARTIFICIAL ORGANS, 2018, 卷号: 42, 期号: 12, 页码: 1196-1205
作者:
Guo, Yaqiong
;
Li, Zhongyu
;
Su, Wentao
;
Wang, Li
;
Zhu, Yujuan
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
Gut-on-a-chip
Caco-2
Intestinal metabolism
Biomimetic
Drug metabolism
Intra-hippocampal administration of orexin receptor antagonists dose-dependently attenuates reinstatement of morphine seeking behavior in extinguished rats
期刊论文
PEPTIDES, 2018, 卷号: 110, 页码: 40-46
作者:
Alizamini, Mirmohammadali Mirramezani
;
Kavianpour, Mohadeseh
;
Karimi-Haghighi, Saeideh
;
Fatahi, Zahra
;
Haghparast, Abbas
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/13
Reward
Orexin
CA1 region of the hippocampus
Reinstatement
Conditioned place preference
Rat
A biomimetic human gut-on-a-chip for modeling drug metabolism in intestine
期刊论文
Artificial organs, 2018, 卷号: 42, 期号: 12, 页码: 1196-1205
作者:
Guo, Yaqiong
;
Li, Zhongyu
;
Su, Wentao
;
Wang, Li
;
Zhu, Yujuan
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/05/08
Gut-on-a-chip
Caco-2
Intestinal metabolism
Biomimetic
Drug metabolism
Age-associated changes in GSH S-transferase gene/proteins in livers of rats
期刊论文
Redox report : communications in free radical research, 2018, 卷号: 23, 期号: 1, 页码: 213-218
作者:
Xu, Shangfu
;
Hou, Dongshun
;
Liu, Jie
;
Ji, Lili
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine
期刊论文
MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52
作者:
Li, Hong
;
Zhao, Lihua
;
Singh, Rani
;
Ham, J. Nina
;
Fadoju, Doris O.
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
Glucagon receptor
Newborn screening
GCGR mutation
Hyperaminoacidemia
Mahvash disease
Pancreatic alpha cell hyperplasia (ACH)
Pancreatic neuroendocrine tumor (PNET)
VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 129, 页码: 177-185
作者:
Zhou, Ling
;
Yi, Yuetao
;
Yuan, Qing
;
Zhang, Jing
;
Li, Youjie
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/08
Vanadyl alginate oligosaccharides
Non-small cell lung cancer
ROS
AKT
PTEN
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp
期刊论文
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
作者:
Xie, Xiaoyan
;
Ma, Jing
;
Xu, Min
;
Zhao, Xinjie
;
Gu, Weiqiong
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
bile acid
hyperglycemic clamp
insulin secretion
type 2 diabetes mellitus
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:
Wang, Jia
;
Gong, Grace Qun
;
Zhou, Yan
;
Lee, Woo-Jeong
;
Buchanan, Christina Maree
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
high throughput screening
PI3 kinase
PI3K alpha H1047R
inhibitors
molecular modeling
Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Meng, Jian
;
Liu, Xiao-Yun
;
Ma, Sheng
;
Zhang, Hua
;
Yu, Song-da
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
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