×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [172]
内容类型
期刊论文 [163]
会议论文 [5]
学位论文 [4]
发表日期
2021 [8]
2020 [7]
2019 [8]
2018 [9]
2017 [3]
2016 [7]
更多...
学科主题
Biochemist... [3]
Chemistry [2]
Pharmacolo... [2]
Biophysics [1]
Psychiatry [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共172条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:
Jin, Tingting
;
Xu, Lei
;
Wang, Peipei
;
Hu, Xiaobei
;
Zhang, Runyuan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/04
Nyctinastic herbs decoction improves para-chlorophenylalanine-induced insomnia by regulating the expression level of neurotransmitters
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 20, 页码: 16
作者:
Yang, Yiwen
;
Wu, You
;
Xu, Peiqin
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
Nyctinastic herbs decoction (NHD)
para-chlorophenylalanine (PCPA)
insomnia
electroencephalograph (EEG)
behavior
neurotransmitters
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F-G protein complex
期刊论文
CELL RESEARCH, 2021, 页码: 3
作者:
Huang, Sijie
;
Xu, Peiyu
;
Tan, Yangxia
;
You, Chongzhao
;
Zhang, Yumu
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:
Wang, Yu
;
He, Yang
;
Yang, Feipu
;
Abame, Melkamu Alemu
;
Wu, Chunhui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/11/04
Structural insights into the lipid and ligand regulation of serotonin receptors
期刊论文
NATURE, 2021, 页码: 25
作者:
Xu, Peiyu
;
Huang, Sijie
;
Zhang, Huibing
;
Mao, Chunyou
;
Zhou, X. Edward
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Polyoxygenated Cembranoids from Soft Coral Lobophytum Crassum and Their Anti-tumoral Activities
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 3, 页码: 640-646
作者:
Yin, Fang-Zhou
;
Huan, Xia-Juan
;
Mudianta, I. Wayan
;
Miao, Ze-Hong
;
Wang, Hong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Soft coral
Lobophytum crassum
Cembranoids
Anti‐
tumoral activity
Stereochemistry
Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus
期刊论文
NEUROSCIENCE LETTERS, 2021, 卷号: 744, 页码: 7
作者:
Abame, Melkamu Alemu
;
He, Yang
;
Wu, Song
;
Xie, Zhifei
;
Zhang, Jian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Synthetic cannabidiol
Depression
Serotonin
Noradrenaline
Nuclear factor kappa B
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
Tan, Xiaoqin
;
Jiang, Xiangrui
;
He, Yang
;
Zhong, Feisheng
;
Li, Xutong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design
Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta
期刊论文
STEROIDS, 2020, 卷号: 161, 页码: 5
作者:
Liu, Jiao
;
Wu, Xin
;
Yang, Min
;
Gu, Yu-Cheng
;
Yao, Li-Gong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
Sinularia erecta
Steroidal derivative
Cytotoxicity
Baeyer-Villiger oxidation
©版权所有 ©2017 CSpace - Powered by
CSpace