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中国医学科学院 北... [65]
内容类型
期刊论文 [49]
会议论文 [8]
学位论文 [8]
发表日期
2019 [6]
2018 [6]
2017 [8]
2016 [8]
2015 [15]
2014 [10]
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专题:中国医学科学院 北京协和医学院
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Injection of alpha-syn-98 Aggregates Into the Brain Triggers alpha-Synuclein Pathology and an Inflammatory Response
期刊论文
2019, 卷号: 12, 页码: 189
作者:
Du, Tingfu
;
Wu, Zhengcun
;
Luo, Haiyu
;
Lu, Shuaiyao
;
Ma, Kaili
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
alpha-syn-98 aggregates
Parkinson's disease
alpha-syn pathology
gliosis
inflammatory response
TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson's disease
期刊论文
2019
作者:
Shao Qian-Hang
;
Chen Ying
;
Li Fang-Fang
;
Wang Shuo
;
Zhang Xiao-Ling
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
MPTP/probenecid mouse model
NF-κB
Parkinson’s disease
Toll-like receptor 4
glial activation
neuroinflammation
oxidative stress
α-synuclein
Nurr1: A vital participant in the TLR4-NF-kappa B signal pathway stimulated by alpha-synuclein in BV-2 cells
期刊论文
2019, 卷号: 144, 页码: 388-399
作者:
Shao, Qian-Hang
;
Yan, Wen-Fen
;
Zhang, Zhao
;
Ma, Kai-Li
;
Peng, Shan-Ying
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Nurr1
alpha-Synuclein
Neuroinflammation
Toll-like receptor 4
Nuclear factor kappa B
A secret that underlies Parkinson's disease: The damaging cycle
期刊论文
2019, 卷号: 129, 页码: 104484
作者:
Sun Feiyi
;
Deng Yulin
;
Han Xiaowei
;
Liu Qingqing
;
Zhang Peng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Damaging cycle
Endogenous neurotoxins
Inflammation
Oxidative stress
Parkinson's disease
α-Synuclein aggregation
NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP
期刊论文
2019, 卷号: 40, 期号: 8, 页码: 991-998
作者:
Chen, Ying
;
Zhang, Qiu-shuang
;
Shao, Qian-hang
;
Wang, Shuo
;
Yuan, Yu-he
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Parkinson's disease
olfactory bulb
alpha-synuclein
TLR4
NF-kappa B
NLRP3
neuroinflammation
MPTP
probenecid
Alpha-synuclein is highly prone to distribution in the hippocampus and midbrain in tree shrews, and its fibrils seed Lewy body-like pathology in primary neurons
期刊论文
2019, 卷号: 116, 页码: 37-45
作者:
Wu, Zheng-Cun
;
Gao, Jia-Hong
;
Du, Ting-Fu
;
Tang, Dong-Hong
;
Chen, Nai-Hong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
Alpha-synuclein
Tree shrew
alpha-Synucleinopathies
Aggregation
Primary neurons
E46K Mutant alpha-Synuclein Is Degraded by Both Proteasome and Macroautophagy Pathway
期刊论文
2018, 卷号: 23, 期号: 11
作者:
Yan, Jia-qing
;
Yuan, Yu-he
;
Chu, Shi-feng
;
Li, Guo-hui
;
Chen, Nai-hong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
alpha-synuclein
E46K
proteasome
chaperon-mediated autophagy
macroautophagy
Prion-like propagation of alpha-synuclein in the gut-brain axis
期刊论文
2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He
;
Chen, Nai-Hong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
alpha-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson's disease
NLRP3 inflammasome activation in the thymus of MPTP-induced Parkinsonian mouse model
期刊论文
2018, 卷号: 288, 页码: 1-8
作者:
Wen, Lu
;
Zhang, Qiu-Shuang
;
Heng, Yang
;
Chen, Ying
;
Wang, Shuo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Parkinson's disease
Thymus
MPTP
Inflammasome
NLRP3
alpha-Synuclein
RTP801 is a critical factor in the neurodegeneration process of A53T-synuclein in a mouse model of Parkinson's disease under chronic restraint stress
期刊论文
2018, 卷号: 175, 期号: 4, 页码: 590-605
作者:
Zhang, Zhao
;
Chu, Shi-Feng
;
Wang, Sha-Sha
;
Jiang, Yi-Na
;
Gao, Yan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Parkinson's disease
RTP801
chronic restraint stress
α-synuclein A53T
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