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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位    发表日期：2014     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 细菌化学趋向性受体聚集体的相互作用 期刊论文 物理化学学报, 2014 余大启; 涂豫海; 来鲁华 收藏  |  浏览/下载：7/0  |  提交时间：2015/11/12 化学趋向性受体 聚集体 分子相互作用 蛋白质-蛋白质对接 分子动力学模拟 Chemoreceptor Assembly Molecular interaction Protein-protein docking Molecular dynamics simulation  Chemoreceptor  Assembly  Molecular interaction  Protein-protein docking  Molecular dynamics simulation   Discovery of binding proteins for a protein target using protein-protein docking-based virtual screening 期刊论文 proteins structure function and bioinformatics, 2014 Zhang, Changsheng; Tang, Bo; Wang, Qian; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/13 protein-protein docking  virtual screening  protein design  protein-protein interaction prediction  binding energy landscape  TNF alpha  COMPUTATIONAL DESIGN  CRYSTAL-STRUCTURE  DRUG DESIGN  TNF-ALPHA  THERAPEUTICS  PERSPECTIVE  PREDICTION  SCAFFOLDS  EVOLUTION  BIOLOGY   In silico search for multi- target therapies for osteoarthritis based on 10 common Huoxue Huayu herbs and potential applications to other diseases 期刊论文 molecular medicine reports, 2014 Zheng, Chun-Song; Zhuang, Zhi-Qiang; Xu, Xiao-Jie; Ye, Jin-Xia; Ye, Hong-Zhi; Li, Xi-Hai; Wu, Guang-Wen; Xu, Hui-Feng; Liu, Xian-Xiang 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/16 osteoarthritis  multi-target therapy  Huoxue Huayu herbs  computational simulation  DRUG DISCOVERY  PROLIFERATION  INFLAMMATION  INHIBITION  MEDICINES  NETWORKS  DATABASE  PATHWAY   Discovery of Novel Secretory Phospholipase A(2) Inhibitors Using Virtual Screen 期刊论文 chemical biology drug design, 2014 Qiu, Shunchen; Chen, Fangjin; Liu, Ying; Lai, Luhua 收藏  |  浏览/下载：7/0  |  提交时间：2015/11/10 continuous fluorescence assay  drug design  novel inhibitor  secretory phospholipase A(2)  virtual screen  INFLAMMATORY DISEASES  INDOLE INHIBITORS  GROUP IIA  POTENT  DOCKING  INACTIVATION  AGENTS  SERUM  MODEL   Molecular docking and molecular dynamics studies on the structure-activity relationship of fluoroquinolone for the HERG channel 期刊论文 分子生物系统, 2014 Luo, Fang; Gu, Jiangyong; Chen, Lirong; Xu, Xiaojie 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 POLYMORPHIC VENTRICULAR-TACHYCARDIA  INTERVAL PROLONGATION  POTASSIUM CHANNEL  FREE-ENERGY  K+ CHANNEL  CARDIAC-ARRHYTHMIA  LIGAND-BINDING  QT INTERVAL  FORCE-FIELD  DRUG   Identification of 1, 4-Dihydrothieno[3 ', 2 ':5, 6] thiopyrano [4, 3-c]pyrazole Derivatives as Human 5-Lipo-oxygenase Inhibitors 期刊论文 chemical biology drug design, 2014 Hu, Jianshu; Zhu, Wei; Meng, Hu; Liu, Ying; Wang, Xin; Hu, Chun 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 bioassay  cross-reactivity  human 5-lipo-oxygenase inhibitors  molecular docking  synthesis  LIPID MEDIATORS  5-LIPOXYGENASE  INFLAMMATION  LIGANDS   A systematic study of chemogenomics of carbohydrates 期刊论文 分子生物系统, 2014 Gu, Jiangyong; Luo, Fang; Chen, Lirong; Yuan, Gu; Xu, Xiaojie 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/10 DRUG DISCOVERY  CHEMICAL SPACE  NETWORK PHARMACOLOGY  POLYPHARMACOLOGY  BIOLOGY  DESIGN  MEDICINES  RESPONSES   Systems pharmacology strategies for anticancer drug discovery based on natural products 期刊论文 分子生物系统, 2014 Luo, Fang; Gu, Jiangyong; Chen, Lirong; Xu, Xiaojie 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 NETWORK PHARMACOLOGY  MEDICINAL-PLANTS  CANCER  AGENTS  MECHANISMS  CHEMOPREVENTION  INHIBITORS  DISORDERS  DIVERSITY  CURCUMIN   Break CDK2/Cyclin E1 Interface Allosterically with Small Peptides 期刊论文 plos one, 2014 Chen, Hao; Zhao, Yunjie; Li, Haotian; Zhang, Dongyan; Huang, Yanzhao; Shen, Qi; Van Duyne, Rachel; Kashanchi, Fatah; Zeng, Chen; Liu, Shiyong 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/11 PROTEIN-PROTEIN INTERACTIONS  CYCLIN-DEPENDENT KINASE-2  MOLECULAR-DYNAMICS  COMPUTATIONAL DESIGN  STRUCTURAL BASIS  BINDING  ACTIVATION  INHIBITORS  MDM2  P53   Traditional Chinese herbs as chemical resource library for drug discovery of anti-infective and anti-inflammatory 期刊论文 journal of ethnopharmacology, 2014 Ding, Weixian; Gu, Jiangyong; Cao, Liang; Li, Na; Ding, Gang; Wang, Zhengzhong; Chen, Lirong; Xu, Xiaojie; Xiao, Wei 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 Traditional Chinese herb  Anti-infection  Anti-inflammatory  Chemical informatics  Network pharmacology  QINGHAOSU ARTEMISININ  NATURAL-PRODUCTS  IN-VITRO  MEDICINE  PHARMACOLOGY  ANTIBACTERIAL  INFECTIONS  ARTESUNATE  NETWORKS  PLANTS