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期刊论文 [64]
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Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways
期刊论文
JOURNAL OF INFLAMMATION RESEARCH, 2021, 卷号: 14
作者:
Ying, Zhen-Hua
;
Li, Hui-Min
;
Yu, Wen-Ying
;
Yu, Chen-Huan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/04/26
isoflavone
glycolysis
Warburg effect
PKM2
JAK/STATs
NF-kappa B
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
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  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Paeonol loaded cyclodextrin metal-organic framework particles for treatment of acute lung injury via inhalation
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 587, 页码: 11
作者:
Li, Haiyan
;
Zhu, Jie
;
Wang, Caifen
;
Qin, Wei
;
Hu, Xiaoxiao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Targeted pulmonary delivery
Cyclodextrin metal-organic frameworks
Dry powder inhalers
Paeonol
Acute lung injury
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
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  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Nimesulide increases the aldehyde oxidase activity of humans and rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Zhou, Lei
;
Pang, Xiao-yan
;
Hou, Xiang-yu
;
Liu, Lu
;
Guo, Zi-tao
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  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
nimesulide
aldehyde oxidase
induction
methotrexate
hepatocytes
pharmacokinetics
drug interaction
Acute and subacute toxicity evaluation of ethanol extract from aerial parts of Epigynum auritum in mice
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2019, 卷号: 131, 页码: 8
作者:
Yang, Meilian
;
Wu, Zihuan
;
Wang, Yudan
;
Kai, Guoyin
;
Njateng, Guy Sedar Singor
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  |  
浏览/下载:58/0
  |  
提交时间:2019/10/28
Epigynum auritum
Acute and subacute oral toxicities
Hematology
Histopathology
Serum biochemistry analysis
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433
作者:
Guo, Zuhao
;
Zhang, Zhuqing
;
Yang, Hong
;
Cao, Danyan
;
Xu, Xiaowei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Tripterygium glycoside fraction n2: Alleviation of DSS-induced colitis by modulating immune homeostasis in mice
期刊论文
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:
Yang, Y. Q.
;
Wu, Y. F.
;
Xu, F. F.
;
Deng, J. B.
;
Wu, L. L.
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  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Tripterygium wilfordii Hook F
Inflammatory bowel disease apoptosis
DSS
T lymphocytes
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