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兰州大学 [32]
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期刊论文 [31]
会议论文 [1]
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2017 [1]
2016 [3]
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pharmacol... [32]
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Design and optimization of thermosensitive nanoemulsion hydrogel for sustained-release of praziquantel
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 卷号: 43, 期号: 1-4, 页码: 558-573
作者:
Cong, ZT
;
Wei, B
;
Wang, Y
;
Li, JC
;
Li, JY
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/05/09
Praziquantel
nanoemulsion
hydrogel
Box-Behnken design
cytotoxicity
pharmacokinetics
Design, synthesis, cytotoxic activity and molecular docking studies of new 20(S)-sulfonylamidine camptothecin derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 115, 页码: 109-120
作者:
Song, ZL
;
Wang, MJ
;
Li, LL
;
Wu, D
;
Wang, YH
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/01/11
Camptothecin
Cytotoxic activity
Molecular docking
Sulfonylamidine
Synthesis
Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 卷号: 10, 页码: 357-370
作者:
Zhang, YF
;
Dai, XJ
;
Yang, Y
;
Chen, XY
;
Wang, T
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/01/09
nemonoxacin
probenecid
cimetidine
clinical pharmacokinetics
drug-drug interaction
Studies on the IC50 of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 1, 页码: 33-42
作者:
Yang, HZ
;
Liu, X
;
Ye, ZL
;
Song, FC
;
Cui, LH
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/11
Gene expression programming
IC50
kinase inhibitors
quantitative structure activity relationship
cell division cycle 7
trisubstituted thiazoles
Design, synthesis and biological evaluation of novel sesquiterpene mustards as potential anticancer agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 94, 页码: 284-297
作者:
Xu, YZ
;
Cu, XY
;
Peng, SJ
;
Fang, JG
;
Zhang, YM
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/01/11
Nitrogen mustard
Sesquiterpene
Anticancer
DNA cross-linking
Dehydrocostuslactone
Costunolide
A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 卷号: 9, 页码: 2947-2959
作者:
Zhang, YH
;
Sun, XL
;
Huang, M
;
Ke, YQ
;
Wang, JH
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/01/09
bispecific immunotoxin
human mesenchymal stem cells
ephrin A1
VEGF(165)
malignant glioma
Design and applications of bifunctional cinnamide derivatives as potential antimycobacterial agents with few hepatotoxic effects
期刊论文
Medicinal Chemistry Research, 2015, 卷号: 24, 期号: 1, 页码: 161-170
作者:
Wu, ZR
;
Zhi, DJ
;
Zheng, LF
;
Li, JY
;
Li, Y
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/12/29
Bifunctional cinnamic acid hydrazide derivatives
Antimycobacterial activity
Caffeic acid
Hepatotoxic effect
Antioxidative property
Design, synthesis, crystal structure, bioactivity, and molecular docking studies of novel sulfonylamidine-derived neonicotinoid analogs
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 12, 页码: 5043-5057
作者:
Yang, L
;
Zhao, YL
;
Zhao, CY
;
Li, HH
;
Wang, MJ
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/12/29
Sulfonylamidine
Acaricidal activity
Insecticidal activity
X-ray diffraction
Molecular docking
Design, Synthesis, Mechanisms of Action, and Toxicity of Novel 20(S)-Sulfonylamidine Derivatives of Camptothecin as Potent Antitumor Agents
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 14, 页码: 6008-6018
作者:
Wang, MJ
;
Liu, YQ
;
Chang, LC
;
Wang, CY
;
Zhao, YL
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/12/29
Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 70, 页码: 631-639
作者:
Zhou, GC
;
Liu, F
;
Wan, JT
;
Wang, J
;
Wang, DC
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/12/14
Fumagillin
Biotinylated fumagillin
Angiogenesis
Cell permeability
Endothelial cell
Cancer cell
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