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湖南中医药大学 [10]
内容类型
期刊论文 [10]
发表日期
2019 [2]
2018 [4]
2017 [3]
2016 [1]
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专题:湖南中医药大学
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TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson's disease.
期刊论文
Acta Pharmacologica Sinica, 2019
作者:
Shao, Qian-Hang
;
Chen, Ying
;
Li, Fang-Fang
;
Wang, Shuo
;
Zhang, Xiao-Ling
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
MPTP/probenecid mouse model
NF-kappaB
Parkinson's disease
Toll-like receptor 4
glial activation
neuroinflammation
oxidative stress
alpha-synuclein
RNAi-mediated knockdown of DJ-1 leads to mitochondrial dysfunction via Akt/GSK-3 beta and JNK signaling pathways in dopaminergic neuron-like cells
期刊论文
Brain research bulletin, 2019, 卷号: 146, 页码: 228-236
作者:
Zhang, Xiao-Ling
;
Wang, Zhen-Zhen
;
Shao, Qian-Hang
;
Zhang, Zhao
;
Li, Lin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Akt
DJ-1
Mitochondrial dysfunction
Nuclear factor erythroid 2 (Nrf2)
c-Jun N-terminal kinase (JNK)
Corrigendum to “Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways” [Molecular Immunology 99 (2018) 115–123] (Molecular Immunology (2018) 99 (115–123), (S0161589018301433) (10.1016/j.molimm.2018.04.014))
期刊论文
Molecular immunology, 2018, 卷号: 101, 页码: 640
作者:
Shao, Qian-Hang
;
Zhang, Xiao-Ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Nurr1: A vital participant in the TLR4-NF-kappa B signal pathway stimulated by alpha-synuclein in BV-2 cells
期刊论文
Neuropharmacology, 2018, 卷号: 144, 页码: 388-399
作者:
Shao, Qian-Hang
;
Yan, Wen-Fen
;
Zhang, Zhao
;
Ma, Kai-Li
;
Peng, Shan-Ying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Nurr1
alpha-Synuclein
Neuroinflammation
Toll-like receptor 4
Nuclear factor kappa B
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult
期刊论文
Toxicology Letters, 2017, 卷号: 271, 期号: Volume 271, 页码: 74-83
作者:
Zhang, Xiao-Ling
;
Yuan, Yu-He
;
Shao, Qian-Hang
;
Wang, Zhen-Zhen
;
Zhu, Cheng-Gen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
8-OHdG
8-hydroxygluanine
ARE
antioxidant response element
GSK3β
glycogen synthase kinase 3β
HO-1
hemeoxygenase-1
LDH
lactate dehydrogenase
MDA
malondialdehyde
NQO1
NADPH quinone oxidoreductase 1
Nrf2
nuclear factor erythroid 2-related factor
PI3K
phosphoinositide-3-kinase
PD
Parkinson’s disease
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TCMs
traditional Chinese medicines
20C
Parkinson’s disease (PD)
DJ-1
Akt
Oxidative stress
Nuclear factor erythroid 2-related factor (Nrf2)
Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
期刊论文
International Immunopharmacology, 2017, 卷号: 49, 页码: 155-160
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Yang, Peng-fei
;
Yuan, Yu-he*
;
Chen, Nai-hong*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
AD
Alzheimer's disease
ANSC
adult neural stem cell
Aβ
amyloid-β protein
CNS
central nervous system
DAMPs
danger-associated molecular patterns
IL-1
interleukin-1
LBs
Lewy bodies
NFTs
neurofibrillary tangles
NLRs
NOD-like receptors
PAMPs
pathogen-associated molecular patterns
PD
Parkinson's disease
PRRs
pattern recognition receptors
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TLRs
toll-like receptors
α-Synuclein
Amyloid-β
Inflammation
NLRP3 inflammasome
Neurodegenerative disease
Synthesis and anti-inflammatory effects of a series of novel 9-O-substituted berberine derivatives
期刊论文
Medicinal Chemistry Research, 2017, 卷号: 26, 期号: 3, 页码: 672-679
作者:
Liu, Zhenbao
;
Wang, Xiaohong
;
Zhang, Hang
;
Zhang, Shanshan
;
Li, Yiqian
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
Berberine derivatives
Carboxylic acid drug
Anti-inflammatory effects
Ear swelling inhibition
Cytokines
Claulansine F promoted the neuronal differentiation of neural stem and progenitor cells through Akt/GSK-3β/β-catenin pathway
期刊论文
European Journal of Pharmacology, 2016, 卷号: 786, 页码: 72-84
作者:
Huang, Ju-yang
;
Ma, Yin-zhong
;
Yuan, Yu-he
;
Zuo, Wei
;
Chu, Shi-feng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Claulansine F
Neuronal differentiation
Akt/GSK-3 beta/beta-catenin
Neural stem/progenitor cells
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