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湖南中医药大学 [12]
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期刊论文 [12]
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2019 [2]
2018 [5]
2017 [2]
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专题:湖南中医药大学
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TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson's disease.
期刊论文
Acta Pharmacologica Sinica, 2019
作者:
Shao, Qian-Hang
;
Chen, Ying
;
Li, Fang-Fang
;
Wang, Shuo
;
Zhang, Xiao-Ling
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
MPTP/probenecid mouse model
NF-kappaB
Parkinson's disease
Toll-like receptor 4
glial activation
neuroinflammation
oxidative stress
alpha-synuclein
RNAi-mediated knockdown of DJ-1 leads to mitochondrial dysfunction via Akt/GSK-3 beta and JNK signaling pathways in dopaminergic neuron-like cells
期刊论文
Brain research bulletin, 2019, 卷号: 146, 页码: 228-236
作者:
Zhang, Xiao-Ling
;
Wang, Zhen-Zhen
;
Shao, Qian-Hang
;
Zhang, Zhao
;
Li, Lin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Akt
DJ-1
Mitochondrial dysfunction
Nuclear factor erythroid 2 (Nrf2)
c-Jun N-terminal kinase (JNK)
Corrigendum to “Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways” [Molecular Immunology 99 (2018) 115–123] (Molecular Immunology (2018) 99 (115–123), (S0161589018301433) (10.1016/j.molimm.2018.04.014))
期刊论文
Molecular immunology, 2018, 卷号: 101, 页码: 640
作者:
Shao, Qian-Hang
;
Zhang, Xiao-Ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Prion-like propagation of α-synuclein in the gut-brain axis
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
CNS
central nervous system
DA
dopamine
DMV
dorsal motor nucleus of the vagus
ENS
enteric nervous system
GI
gastrointestinal
IL-1
interleukin-1
LBs
Lewy bodies
LPS
lipopolysaccharide
LAG3
lymphocyte-activation gene 3
MPTP
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
P301L
mutant Tau
PD
Parkinson's disease
PNS
peripheral nervous system
ROS
reactive oxygen species
SCFA
short chain fatty acids
SN
substantia nigra
TH
Tyrosine hydroxylase
TLR 2
Toll-like receptor 2
TNTs
tunneling nanotubes
α-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson’s disease
Nurr1: A vital participant in the TLR4-NF-kappa B signal pathway stimulated by alpha-synuclein in BV-2 cells
期刊论文
Neuropharmacology, 2018, 卷号: 144, 页码: 388-399
作者:
Shao, Qian-Hang
;
Yan, Wen-Fen
;
Zhang, Zhao
;
Ma, Kai-Li
;
Peng, Shan-Ying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Nurr1
alpha-Synuclein
Neuroinflammation
Toll-like receptor 4
Nuclear factor kappa B
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult
期刊论文
Toxicology Letters, 2017, 卷号: 271, 期号: Volume 271, 页码: 74-83
作者:
Zhang, Xiao-Ling
;
Yuan, Yu-He
;
Shao, Qian-Hang
;
Wang, Zhen-Zhen
;
Zhu, Cheng-Gen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
8-OHdG
8-hydroxygluanine
ARE
antioxidant response element
GSK3β
glycogen synthase kinase 3β
HO-1
hemeoxygenase-1
LDH
lactate dehydrogenase
MDA
malondialdehyde
NQO1
NADPH quinone oxidoreductase 1
Nrf2
nuclear factor erythroid 2-related factor
PI3K
phosphoinositide-3-kinase
PD
Parkinson’s disease
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TCMs
traditional Chinese medicines
20C
Parkinson’s disease (PD)
DJ-1
Akt
Oxidative stress
Nuclear factor erythroid 2-related factor (Nrf2)
Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
期刊论文
International Immunopharmacology, 2017, 卷号: 49, 页码: 155-160
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Yang, Peng-fei
;
Yuan, Yu-he*
;
Chen, Nai-hong*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
AD
Alzheimer's disease
ANSC
adult neural stem cell
Aβ
amyloid-β protein
CNS
central nervous system
DAMPs
danger-associated molecular patterns
IL-1
interleukin-1
LBs
Lewy bodies
NFTs
neurofibrillary tangles
NLRs
NOD-like receptors
PAMPs
pathogen-associated molecular patterns
PD
Parkinson's disease
PRRs
pattern recognition receptors
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TLRs
toll-like receptors
α-Synuclein
Amyloid-β
Inflammation
NLRP3 inflammasome
Neurodegenerative disease
Ezetimibe-mediated protection of vascular smooth muscle cells from cholesterol accumulation through the regulation of lipid metabolism-related gene expression.
期刊论文
PHARMACOLOGY, 2014, 卷号: 94, 期号: 5-6, 页码: 214-222
作者:
Gong, Yong-Zhen
;
Sun, Shao-Wei
;
Yuan, Hao-Yu
;
Xie, Xue-Jiao
;
Tuo, Qin-Hui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Ezetimibe
Liver X receptor
Sterol-regulatory element binding protein 1
ATP-binding cassette transporter A1
Caveolin-1
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