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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu
收藏  |  浏览/下载:237/0  |  提交时间:2020/12/24
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun
收藏  |  浏览/下载:68/0  |  提交时间:2020/12/24
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes 期刊论文
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:  Dou, Hui-Xia;  Wang, Ting;  Su, Hai-Xia;  Gao, Ding-Ding;  Xu, Ye-Chun
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/01
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 (vol 154, pg 44, 2018) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 235-236
作者:  Gao, Ding-Ding;  Dou, Hui-Xia;  Su, Hai-Xia;  Zhang, Ming-Ming;  Wang, Ting
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 44-59
作者:  Gao, Ding-Ding;  Dou, Hui-Xia;  Su, Hai-Xia;  Zhang, Ming-Ming;  Wang, Ting
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:  Chen, Yu-ting;  Chen, Wu-yan;  Huang, Xiao-tian;  Xu, Ye-chun;  Zhang, Hai-yan
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells 期刊论文
Oncology reports, 2015, 卷号: 34, 期号: 3, 页码: 1543-8
作者:  Ye, Yan;  Chao, Xiao-Juan;  Wu, Jin-Feng;  Cheng, Brian Chi-Yan;  Su, Tao
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Xanthones from Swertia mussotii as Multitarget-Directed Antidiabetic Agents 期刊论文
CHEMMEDCHEM, 2014, 卷号: 9, 期号: 7, 页码: 1374-1377
作者:  Zheng, Huan-Huan;  Luo, Cui-Ting;  Chen, Heru;  Lin, Juan-Na;  Ye, Chun-Ling
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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