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科研机构
上海药物研究所 [29]
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期刊论文 [29]
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2021 [3]
2020 [5]
2019 [4]
2018 [8]
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Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Lu, Qiu-kai
;
Fan, Chen
;
Xiang, Cai-gui
;
Wu, Bing
;
Lu, Hui-min
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/06/11
PDE4
apremilast
skin fibrosis
macrophages
Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts
Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 1, 页码: 70-80
作者:
Pan Hui-Qin
;
Zhou Heng
;
Miao Shui
;
Guo De-An
;
Zhang Xiao-Li
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Plant metabolomics
Insecticide
Metabolite variation
Lonicerae Japonicae Flos
Identification of SARS-CoV-2 entry inhibitors among already approved drugs
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Yang, Li
;
Pei, Rong-juan
;
Li, Heng
;
Ma, Xin-na
;
Zhou, Yu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/24
COVID-19
SARS-CoV-2
virus entry inhibitors
high throughput screening assay
approved drug library
histamine receptor antagonists
clemastine
Polyprenylated acylphloroglucinols as deubiquitinating protease USP7 inhibitors from Hypericum hookerianum
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 5
作者:
Wang, Qi-Qi
;
Wang, Xiao-Dong
;
Wu, Ling-Zhi
;
Fang, Qiang-Qiang
;
Liu, Ya-Nan
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  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 99, 页码: 5
作者:
Wang, Xiao-Feng
;
Zhu, Zhengdan
;
Hao, Ting-Ting
;
Fang, Qiang-Qiang
;
Jiang, Kun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Sophora alopecuroides
Alkaloids
Cl-containing matrines
Absolute configuration
Immunosuppressive activity
Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase
期刊论文
NUCLEIC ACIDS RESEARCH, 2020, 卷号: 48, 期号: 5, 页码: 2709-2722
作者:
Nguyen, Phuong D. M.
;
Zheng, Jie
;
Gremminger, Thomas J.
;
Qiu, Liming
;
Zhang, Dong
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  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
A new recombinant MS-superoxide dismutase alleviates 5-fluorouracil-induced intestinal mucositis in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 348-357
作者:
Yan, Xiao-xia
;
Li, Hai-long
;
Zhang, Yi-ting
;
Wu, Shou-yan
;
Lu, Heng-lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
new dinorditerpenoids from Flueggea virosa
期刊论文
FITOTERAPIA, 2019, 卷号: 133, 页码: 96-101
作者:
Wang, Xiao-Feng
;
Liu, Fei-Fei
;
Zhu, Zhengdan
;
Fang, Qiang-Qiang
;
Qu, Shi-Jin
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/04/02
Flueggea Virosa
13-methyl-ent-podocarpane
Securinega Alkaloids
Tddft Ecd
Anti-hcv
Flueggenoids A - E, new dinorditerpenoids from Flueggea virosa
期刊论文
FITOTERAPIA, 2019, 卷号: 133, 页码: 96-101
作者:
Wang, Xiao-Feng
;
Liu, Fei-Fei
;
Zhu, Zhengdan
;
Fang, Qiang-Qiang
;
Qu, Shi-Jin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Flueggea virosa
13-Methyl-ent-podocarpane
Securinega alkaloids
TDDFT ECD
Anti-HCV
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