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STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Wu, Bing;  Xu, Meng-meng;  Fan, Chen;  Feng, Chun-lan;  Lu, Qiu-kai
收藏  |  浏览/下载:59/0  |  提交时间:2022/01/18
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载:40/0  |  提交时间:2021/08/17
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Lu, Qiu-kai;  Fan, Chen;  Xiang, Cai-gui;  Wu, Bing;  Lu, Hui-min
收藏  |  浏览/下载:58/0  |  提交时间:2021/06/11
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen
收藏  |  浏览/下载:148/0  |  提交时间:2021/05/24
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文
CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24
作者:  Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang
收藏  |  浏览/下载:40/0  |  提交时间:2021/05/24
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants 期刊论文
ADVANCES IN THERAPY, 2020, 页码: 20
作者:  He, Xin;  Qiu, Jin-Chun;  Lu, Ke-Yu;  Guo, Hong-Li;  Li, Ling
收藏  |  浏览/下载:30/0  |  提交时间:2020/12/24
Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:  Duan, Jia;  Shen, Dan-dan;  Zhou, X. Edward;  Bi, Peng;  Liu, Qiu-feng
收藏  |  浏览/下载:23/0  |  提交时间:2020/12/24
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:  Qiu, Yunguang;  Huang, Lu;  Fu, Jie;  Han, Chenxia;  Fang, Jing
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载:92/0  |  提交时间:2020/07/01
Unusual ent-Labdane Diterpenoid Dimers and their Selective Activation of TRPV Channels 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 21, 页码: 13595-13603
作者:  Gao, Suyu;  Wang, Dun;  Chai, Hao;  Xu, Jiamin;  Li, Tianyu
收藏  |  浏览/下载:47/0  |  提交时间:2020/07/01


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