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科研机构
上海药物研究所 [7]
内容类型
期刊论文 [7]
发表日期
2020 [1]
2018 [1]
2017 [3]
2016 [1]
2015 [1]
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Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats
期刊论文
NEUROSCIENCE BULLETIN, 2020, 卷号: 36, 期号: 4, 页码: 333-345
作者:
Gu, Pan
;
Xu, Zi-Hao
;
Cao, Yu-Ze
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Epilepsy
Synchrotron radiation
3D
Angioarchitecture
Blood vessel
Remodeling
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands
期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Chen, Li-Li
;
Pan, You-Lu
;
Xie, Xiao-Yu
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
cannabinoids
CB1R
CB2R
heteroaryl pyrimidines
heteroaryl triazines
ligands
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Development of Quinazoline/Pyrimidine-2,4(1H,3H)-diones as Agonists of Cannabinoid Receptor Type 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 6, 页码: 678-681
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Pan, You-Lu
;
Chen, Li-Li
;
Xie, Xin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Cannabinoid receptors
CB2 agonist
structure-activity relationship
molecular modeling
An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional liquid chromatography/linear ion-trap-Orbitrap mass spectrometry, high-resolution diagnostic product ions/neutral loss filtering and liquid chromatography-solid phase extraction-nuclear magnetic resonance
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2017, 卷号: 1491, 页码: 87-97
作者:
Yao, Chang-liang
;
Yang, Wen-zhi
;
Si, Wei
;
Shen, Yao
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Enhanced targeted identification strategy
Offline two-dimensional liquid
chromatography
Diagnostic product ions filtering
Liquid chromatography-solid phase
extraction-nuclear magnetic resonance
Carthamus tinctorius
Flavonoid O-glycoside
Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 3, 页码: 415-424
作者:
Ma, Lei-lei
;
Wu, Zhi-tao
;
Wang, Le
;
Zhang, Xue-feng
;
Wang, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
leflunomide
hepatotoxicity
CYPs
teriflunomide
aminobenzotriazole
proadifen
NTCP
cholestasis
Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine
期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 12, 页码: 1138-1146
作者:
Chen, Chen
;
Wu, Zhi-Tao
;
Ma, Lei-Lei
;
Ni, Xuan
;
Lin, Yun-Fei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Berberine
organic cation transporter
organic anion-transporting polypeptides
primary hepatocytes
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