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科研机构
上海药物研究所 [31]
内容类型
期刊论文 [29]
会议论文 [2]
发表日期
2020 [4]
2018 [1]
2017 [3]
2015 [1]
2014 [7]
2013 [4]
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Meroterpenoids with diverse structures and anti-inflammatory activities from Rhododendron anthopogonoides
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 180, 页码: 11
作者:
Shi, Qing
;
Li, Teng-Teng
;
Wu, Yong-Mei
;
Sun, Xin-Yu
;
Lei, Chun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
Rhododendron anthopogonoides Maxim
Ericaceae
Meroterpenoids
Anthoponoids A-I
Daurichromene D
Anti-inflammation
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 5, 页码: 488-493
作者:
Hu, Xiao
;
Yu, Mei-Hua
;
Yan, Gui-Rui
;
Wang, He-Yao
;
Hou, Ai-Jun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Morus nigra
Moraceae
isoprenylated phenolic compounds
nigrasin K
mushroom tyrosinase
Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542
作者:
Xie, Qin
;
Chen, Hui
;
Ai, Jing
;
Gao, Ying-lei
;
Geng, Mei-yu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET
Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047
作者:
Yang, Zhong-min
;
Liao, Xue-mei
;
Chen, Yi
;
Shen, Yan-yan
;
Yang, Xin-ying
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
homologous recombination repair defects
breast cancer
ovarian cancer
TALEN
combined biomarker
simmiparib
olaparib
Amino acids as co-amorphous excipients for tackling the poor aqueous solubility of valsartan
期刊论文
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2017, 卷号: 22, 期号: 1, 页码: 69-76
作者:
Huang, Ying
;
Zhang, Qi
;
Wang, Jian-Rong
;
Lin, Kai-Lei
;
Mei, Xuefeng
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Amino acid
co-amorphous
intrinsic dissolution rate
small molecular excipients
solubility
valsartan
Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization
期刊论文
MOLECULES, 2015, 卷号: 20, 期号: 6, 页码: 10342-10359
作者:
Yan, Wenzhong
;
Qing, Jie
;
Mei, Hanbing
;
Mao, Fei
;
Huang, Jin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
CypA
small molecule inhibitor
anti-HCV
O-acylation
The E3 ligase APC/C-Cdh1 regulates MEF2A-dependent transcription by targeting SUMO-specific protease 2 for ubiquitination and degradation
期刊论文
CELL CYCLE, 2014, 卷号: 13, 期号: 24, 页码: 3892-3902
作者:
Lu, Han
;
Liu, Bin
;
Zhang, Fu-Jun
;
Zhang, Jin
;
Dong, Rong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
activity-dependent stimuli
APC-Cdh1
MEF2A
SENP2
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