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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
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2021 [2]
2020 [2]
2019 [1]
2017 [1]
2014 [1]
2013 [2]
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Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:148/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Liu, Xiao-yun
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Zhang, Yi-fan
;
Zhou, Jia-lan
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
alflutinib
AST5902
metabolism
enzyme induction
drug-drug interaction
Cyclodextrin-Based Peptide Self-Assemblies (Spds) That Enhance Peptide-Based Fluorescence Imaging and Antimicrobial Efficacy
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 4, 页码: 1925-1932
作者:
Jiao, Jin-Biao
;
Wang, Guan-Zhen
;
Hu, Xi-Le
;
Zang, Yi
;
Maisonneuve, Stephane
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
期刊论文
NATURE, 2019, 卷号: 567, 期号: 7747, 页码: 257-+
作者:
Jiang, Ying
;
Sun, Aihua
;
Zhao, Yang
;
Ying, Wantao
;
Sun, Huichuan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
Four Phragmalin Orthoesters from the Chinese Mangrove Xylocarpus granatum
期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 11, 页码: 949-954
作者:
Zhou, Zhen-Fang
;
Kong, Ling-Yi
;
Kurtan, Tibor
;
Liu, Hai-Li
;
Mandi, Attila
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Meliaceae
Xylocarpus granatum
phragmalin orthoesters
configuration determination
biological activity
Capturing intercellular sugar-mediated ligand-receptor recognitions via a simple yet highly biospecific interfacial system
期刊论文
SCIENTIFIC REPORTS, 2013, 卷号: 3
作者:
Li, Zhen
;
Deng, Si-Si
;
Zang, Yi
;
Gu, Zhen
;
He, Xiao-Peng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
Phase I study on the pharmacokinetics and tolerance of ZT-1, a prodrug of huperzine A, for the treatment of Alzheimer's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 7, 页码: 976-982
作者:
Jia, Jing-ying
;
Zhao, Qian-hua
;
Liu, Yun
;
Gui, Yu-zhou
;
Liu, Gang-yi
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
ZT-1
huperzine A
prodrug
AChE inhibitor
drug tolerance
pharmacokinetics
Alzheimer's disease
Periplocoside A prevents experimental autoimmune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2009, 卷号: 30, 期号: 8, 页码: 1144-1152
作者:
Zhang, Jing
;
Ni, Jia
;
Chen, Zhen-hua
;
Li, Xin
;
Zhang, Ru-jun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
P sepium Bge
Periplocoside A
experimental autoimmune encephalomyelitis
Th17 cells
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