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Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:  Tao, Hongru;  Wang, Jun;  Lu, Wenchao;  Zhang, Rukang;  Xie, Yiqian
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/01
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:  Lu, Wenchao;  Xiong, Huan;  Chen, Yu;  Wang, Chen;  Zhang, Hao
收藏  |  浏览/下载:139/0  |  提交时间:2019/01/08
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:  Zhang, Rukang;  Wang, Jiang;  Zhao, Liang;  Liu, Shien;  Du, Daohai
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751
作者:  Xiong, Huan;  Han, Jie;  Wang, Jun;  Lu, Wenchao;  Wang, Chen
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:  Song, Yakai;  Li, Linjuan;  Chen, Yantao;  Liu, Jingqiu;  Xiao, Senhao
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3
作者:  Ding, Hong;  Lu, Wen Chao;  Hu, Jun Chi;  Liu, Yu-Chih;  Zhang, Chen Hua
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1 期刊论文
ACS CHEMICAL BIOLOGY, 2018, 卷号: 13, 期号: 3, 页码: 772-781
作者:  Ye, Fei;  Kong, Xiangqian;  Zhang, Hao;  Liu, Yan;  Shao, Zhiyuan
收藏  |  浏览/下载:35/0  |  提交时间:2019/01/08
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
作者:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng
收藏  |  浏览/下载:113/0  |  提交时间:2019/01/08
Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 7, 页码: 1677-1690
作者:  Xing, Jing;  Lu, Wenchao;  Liu, Rongfeng;  Wang, Yulan;  Xie, Yiqian
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08


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