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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791 作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 GPR40 agonist  2,3-Dihydrobenzo[b][1,4]dioxine  Insulin secretion  Type 2 diabetes mellitus   Identification of a cellularly active SIRT6 allosteric activator 期刊论文 NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+ 作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin 收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08 Low-frequency repetitive transcranial magnetic stimulation inhibits the development of methamphetamine-induced conditioned place preference 期刊论文 BEHAVIOURAL BRAIN RESEARCH, 2018, 卷号: 353, 页码: 129-136 作者:  Wu, Xue-Qing;  Zan, Gui-Ying;  Ju, Yun-Yue;  Chen, Tian-Zhen;  Guo, Liu-Bin 收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08 Methamphetamine  rTMS  CPP  Dorsolateral striatum  GABA(B)R1   Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 17, 页码: 10158-10165 作者:  Zhang, Shuaibing;  Huang, Ying;  He, Shijun;  Chen, Heping;  Wu, Bin 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 The mimics of N-epsilon-acyl-lysine derived from cysteine as sirtuin inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2375-2378 作者:  Wang, Chun;  Wang, Fang;  Chen, Xiaoxue;  Zou, Yefang;  Zhu, Hong 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 L-Cysteine  The mimics of lysine  Mechanism-based inhibitors  Sirtuin inhibitors  SIRT2 inhibitors   Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers 期刊论文 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Li, Xiaojiao;  Liu, Ca;  Zhu, Xiaoxue;  Wei, Haijing;  Zhang, Hong 收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08 vicagrel  pharmacokinetics  pharmacodynamics  safety  clopidogrel   Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文 Acta pharmacologica Sinica, 2018 作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Access to Spiroindolines and Spirodihydrobenzofurans via Pd-Catalyzed Domino Heck Spiroyclization through C-H Activation and Carbene Insertion 期刊论文 ORGANIC LETTERS, 2018, 卷号: 20, 期号: 9, 页码: 2728-2732 作者:  Liu, Jian-Guo;  Chen, Wen-Wen;  Gu, Chang-Xue;  Xu, Bin;  Xu, Ming-Hua 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Activation of AhR with nuclear IKK alpha regulates cancer stem-like properties in the occurrence of radioresistance 期刊论文 CELL DEATH & DISEASE, 2018, 卷号: 9 作者:  Yan, Bin;  Liu, Shuang;  Shi, Ying;  Liu, Na;  Chen, Ling 收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08 ACC to Dorsal Medial Striatum Inputs Modulate Histaminergic Itch Sensation 期刊论文 JOURNAL OF NEUROSCIENCE, 2018, 卷号: 38, 期号: 15, 页码: 3823-3839 作者:  Lu, Yu-Chen;  Wang, Yu-Jun;  Lu, Bin;  Chen, Ming;  Zheng, Ping 收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08 anterior cingulate cortex  B5-I neurons  brain neural circuit  dorsal medial striatum  itch