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Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants 期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:  Mao, Xiao-Yuan*;  Jin, Ming-Zhu;  Chen, Jin-Fei*;  Zhou, Hong-Hao;  Jin, Wei-Lin*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
PD  Parkinson's disease  AD  Alzheimer's disease  EGCG  (−)-Epigallocatechin-3-gallate  NRF2  NF-E2-related factor 2  ROS  reactive oxygen species  H2O2  hydrogen peroxide  ER  endoplasmic reticulum  GPX  glutathione-peroxidase  NOX  NADPH oxidases (NOXs)  LOX  lipoxygenases  ERK  extracellular signal-regulated kinase  JNK  c-Jun amino-terminal kinase  MAPK  mitogen-activated protein kinase  HNE  4-hydroxy-2-nonenol  ARE  antioxidant responsive element  GST  glutathione S-transferase  IFNγ  interferon-γ  LPS  lipopolysaccharide  SOD  superoxide dismutase  TNF-α  tumor necrosis factor-α  APP  β-amyloid precursor protein  SAM  S-adenosylmethionine  MAT  methionine adenosyltransferase  SAH  Sadenosyl homocysteine  MT  methyltransferases  BDNF  brain-derived neurotrophic factor  Nutraceuticals  Neuroprotection  Anti-cancer  ROS addiction  Ferroptosis  Oxidative stress  
Osteocalcin Induces Proliferation via Positive Activation of the PI3K/Akt, P38 MAPK Pathways and Promotes Differentiation Through Activation of the GPRC6A-ERK1/2 Pathway in C2C12 Myoblast Cells 期刊论文
Cellular Physiology and Biochemistry, 2017, 卷号: 43, 期号: 3, 页码: 1100-1112
作者:  Liu, Suifeng;  Gao, Feng;  Wen, Lei;  Ouyang, Min;  Wang, Yi
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
MALAT1 participates in ultraviolet B-induced photo-aging via regulation of the ERK/MAPK signaling pathway 期刊论文
Molecular Medicine Reports, 2017, 卷号: 15, 期号: 6, 页码: 3977-3982
作者:  Lei, Li;  Zeng, Qinghai;  Lu, Jianyun;  Ding, Shu;  Xia, Fang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK/MAPK 期刊论文
OncoTargets and Therapy, 2017, 卷号: 10, 页码: 1423-1431
作者:  Chen, Po;  Xu, Wentao;  Luo, Yi;  Zhang, Yi;  He, Yi
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling 期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:  Liu, Jianxin;  Tang, Jinshan;  Zuo, Yihan;  Yu, Yang;  Luo, Pei
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/03
NO  nitric oxide  PGE2  prostaglandin E2  NSAIDs  non-steroidal anti-inflammatory drugs  qRT-PCR  quantitative real-time polymerase chain reaction  LPS  lipopolysaccharide  IFN-γ  interferon γ  G-CSF  granulocyte colony stimulating factor  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  IL-6  interleukin-6  MCP-1  monocyte chemoattractant protein-1  NF-κB  Nuclear factor-κB  IκB  inhibitory protein  IKK  IκB kinase  RPS3  ribosomal protein S3  iNOS  inducible nitric oxide synthase  COX-2  cyclooxygenase-2  PGESs  prostaglandin E2 synthases  mPGES-1  microsomal prostaglandin synthetase-1  mPGES-2  microsomal prostaglandin E synthase-2  cPGES  cytosolic prostaglandin E synthase  MAPK  mitogen-activated protein kinases  ERK  extracellular signal-regulated kinase  JNK  c- Jun N-terminal kinase  PGI2  prostacyclin I2  PGD2  prostaglandin D2  PGF2α  prostaglandin F2α  TXA2  thromboxane A2  Stauntoside B (PubChem CID: 101010462)  Stauntoside B  Cynanchi stauntonii  Lipopolysaccharide  Anti-inflammatory activity  NF-κB  MAPK  
The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 2, 页码: e0149822
作者:  Teng, Jia-An;  Wu, San-Gang;  Chen, Jia-Xin;  Li, Qiang;  Peng, Fang
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells 期刊论文
Journal of Hematology & Oncology, 2016, 卷号: 9, 期号: 1, 页码: 130
作者:  Wang, Zeyou;  Guo, Qin;  Wang, Rong;  Xu, Gang;  Li, Peiyao
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
Icariin stimulates the proliferation of rat bone mesenchymal stem cells via ERK and p38 MAPK signaling 期刊论文
International Journal of Clinical and Experimental Medicine, 2015, 卷号: 8, 期号: 5, 页码: 7125-7133
作者:  Qin, Shuyan;  Zhou, Wei;  Liu, Shaoying;  Chen, Puxiang*;  Wu, Hongjin
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
Fluorofenidone Attenuates Oxidative Stress and Renal Fibrosis in Obstructive Nephropathy via Blocking NOX2 (gp91phox) Expression and Inhibiting ERK/MAPK Signaling Pathway 期刊论文
Kidney and Blood Pressure Research, 2015, 卷号: 40, 期号: 1, 页码: 89-99
作者:  Qin, Jiao;  Mei, Wen-Juan;  Xie, Yan-Yun;  Huang, Ling;  Yuan, Qiong-Jing
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
The effect of Chaihu-Shugan-San and its components on the expression of ERK5 in the hippocampus of depressed rats 期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 2, 页码: 320-326
作者:  Qiu, Juan*;  Hu, Sui-Yu;  Zhang, Chun-Hu;  Shi, Guang-Qing;  Wang, Su-e
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03


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