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科研机构
中南大学 [17]
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期刊论文 [17]
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2018 [1]
2017 [3]
2016 [3]
2015 [2]
2014 [2]
2013 [4]
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Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants
期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:
Mao, Xiao-Yuan*
;
Jin, Ming-Zhu
;
Chen, Jin-Fei*
;
Zhou, Hong-Hao
;
Jin, Wei-Lin*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
PD
Parkinson's disease
AD
Alzheimer's disease
EGCG
(−)-Epigallocatechin-3-gallate
NRF2
NF-E2-related factor 2
ROS
reactive oxygen species
H2O2
hydrogen peroxide
ER
endoplasmic reticulum
GPX
glutathione-peroxidase
NOX
NADPH oxidases (NOXs)
LOX
lipoxygenases
ERK
extracellular signal-regulated kinase
JNK
c-Jun amino-terminal kinase
MAPK
mitogen-activated protein kinase
HNE
4-hydroxy-2-nonenol
ARE
antioxidant responsive element
GST
glutathione S-transferase
IFNγ
interferon-γ
LPS
lipopolysaccharide
SOD
superoxide dismutase
TNF-α
tumor necrosis factor-α
APP
β-amyloid precursor protein
SAM
S-adenosylmethionine
MAT
methionine adenosyltransferase
SAH
Sadenosyl homocysteine
MT
methyltransferases
BDNF
brain-derived neurotrophic factor
Nutraceuticals
Neuroprotection
Anti-cancer
ROS addiction
Ferroptosis
Oxidative stress
Osteocalcin Induces Proliferation via Positive Activation of the PI3K/Akt, P38 MAPK Pathways and Promotes Differentiation Through Activation of the GPRC6A-ERK1/2 Pathway in C2C12 Myoblast Cells
期刊论文
Cellular Physiology and Biochemistry, 2017, 卷号: 43, 期号: 3, 页码: 1100-1112
作者:
Liu, Suifeng
;
Gao, Feng
;
Wen, Lei
;
Ouyang, Min
;
Wang, Yi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Differentiation
ERK1/2
GPRC6A
Myoblast
Osteocalcin
P38 MAPK
PI3K/Akt
Proliferation
MALAT1 participates in ultraviolet B-induced photo-aging via regulation of the ERK/MAPK signaling pathway
期刊论文
Molecular Medicine Reports, 2017, 卷号: 15, 期号: 6, 页码: 3977-3982
作者:
Lei, Li
;
Zeng, Qinghai
;
Lu, Jianyun
;
Ding, Shu
;
Xia, Fang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
long non-coding RNAs
metastasis-associated lung adenocarcinoma transcript 1
photo-aging
matrix metalloproteinase-1
mitogen-activated protein kinase
reactive oxygen species
MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK/MAPK
期刊论文
OncoTargets and Therapy, 2017, 卷号: 10, 页码: 1423-1431
作者:
Chen, Po
;
Xu, Wentao
;
Luo, Yi
;
Zhang, Yi
;
He, Yi
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
ERK2
apoptosis
breast cancer
cell cycle
microRNA 543
proliferation
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling
期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:
Liu, Jianxin
;
Tang, Jinshan
;
Zuo, Yihan
;
Yu, Yang
;
Luo, Pei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/03
NO
nitric oxide
PGE2
prostaglandin E2
NSAIDs
non-steroidal anti-inflammatory drugs
qRT-PCR
quantitative real-time polymerase chain reaction
LPS
lipopolysaccharide
IFN-γ
interferon γ
G-CSF
granulocyte colony stimulating factor
TNF-α
tumor necrosis factor-α
IL-1β
interleukin-1β
IL-6
interleukin-6
MCP-1
monocyte chemoattractant protein-1
NF-κB
Nuclear factor-κB
IκB
inhibitory protein
IKK
IκB kinase
RPS3
ribosomal protein S3
iNOS
inducible nitric oxide synthase
COX-2
cyclooxygenase-2
PGESs
prostaglandin E2 synthases
mPGES-1
microsomal prostaglandin synthetase-1
mPGES-2
microsomal prostaglandin E synthase-2
cPGES
cytosolic prostaglandin E synthase
MAPK
mitogen-activated protein kinases
ERK
extracellular signal-regulated kinase
JNK
c- Jun N-terminal kinase
PGI2
prostacyclin I2
PGD2
prostaglandin D2
PGF2α
prostaglandin F2α
TXA2
thromboxane A2
Stauntoside B (PubChem CID: 101010462)
Stauntoside B
Cynanchi stauntonii
Lipopolysaccharide
Anti-inflammatory activity
NF-κB
MAPK
The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus
期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 2, 页码: e0149822
作者:
Teng, Jia-An
;
Wu, San-Gang
;
Chen, Jia-Xin
;
Li, Qiang
;
Peng, Fang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Insulin,Colorectal cancer,Type 2 diabetes,MAPK signaling cascades,Mouse models,Apoptosis,Colon,Insulin signaling
The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells
期刊论文
Journal of Hematology & Oncology, 2016, 卷号: 9, 期号: 1, 页码: 130
作者:
Wang, Zeyou
;
Guo, Qin
;
Wang, Rong
;
Xu, Gang
;
Li, Peiyao
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/03
Leucine-rich repeat
D domain
CD domain
ERK1/2
MAPK
Icariin stimulates the proliferation of rat bone mesenchymal stem cells via ERK and p38 MAPK signaling
期刊论文
International Journal of Clinical and Experimental Medicine, 2015, 卷号: 8, 期号: 5, 页码: 7125-7133
作者:
Qin, Shuyan
;
Zhou, Wei
;
Liu, Shaoying
;
Chen, Puxiang*
;
Wu, Hongjin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
ERK
Icariin
bone mesenchymal stem cells
p38 MAPK
Fluorofenidone Attenuates Oxidative Stress and Renal Fibrosis in Obstructive Nephropathy via Blocking NOX2 (gp91phox) Expression and Inhibiting ERK/MAPK Signaling Pathway
期刊论文
Kidney and Blood Pressure Research, 2015, 卷号: 40, 期号: 1, 页码: 89-99
作者:
Qin, Jiao
;
Mei, Wen-Juan
;
Xie, Yan-Yun
;
Huang, Ling
;
Yuan, Qiong-Jing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Fluorofenidone
Obstructive nephropathy
NOX2 (gp91phox)
ERK
Losartan
The effect of Chaihu-Shugan-San and its components on the expression of ERK5 in the hippocampus of depressed rats
期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 2, 页码: 320-326
作者:
Qiu, Juan*
;
Hu, Sui-Yu
;
Zhang, Chun-Hu
;
Shi, Guang-Qing
;
Wang, Su-e
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
CSS
Chaihu-Shugan-San
TCM
traditional Chinese medicines
CUMS
chronic unpredictable mild stress
ERK
extracellular signal-regulated kinase
p-ERK
phosphorylation-ERK5
MAPK
mitogen-activated protein kinase
BDNF
brain-derived neurotrophic factor.
Chaihu-Shugan-San
Antidepressant-like activity
Extracellular signal-regulated kinase
Hippocampus
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