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科研机构
上海药物研究所 [15]
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期刊论文 [15]
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2021 [1]
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2018 [5]
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A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1653, 页码: 12
作者:
Zhu, Haodong
;
Wu, Xingdong
;
Huo, Jiangyan
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2021/11/04
Gastrodia Rhizoma
Multidimensional data acquisition
Offline 2D-LC-IMS-DIA MS
MS
Neutral loss (NLs)
Collision cross section (CCS)
Targeting beta 2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2+
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 卷号: 9, 期号: 6, 页码: 1293-+
作者:
Li, Shirong
;
Dai, Zhi
;
Yang, Dong
;
Li, Wenxuan
;
Dai, Hongjuan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
ATP1B2
Na+/K+-ATPase
glioblastoma
digoxin
An enhanced strategy integrating offline two-dimensional separation and step-wise precursor ion list-based raster-mass defect filter: Characterization of indole alkaloids in five botanical origins of Uncariae Ramulus Cum Unicis as an exemplary application
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1563, 页码: 124-134
作者:
Pan, Huiqin
;
Yao, Changliang
;
Yang, Wenzhi
;
Yao, Shuai
;
Huang, Yong
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Offline comprehensive 2D LC
Precursor ion list
Mass defect filter
Uncariae Ramulus Cum Unicis
Indole alkaloid
Structural studies and drug discovery of G protein-coupled receptors
期刊论文
Kexue Tongbao/Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1361-1373
作者:
Yang, Zhenlin
;
Wu, Beili
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  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1548, 页码: 64-75
作者:
Shi, Xiaojian
;
Yang, Wenzhi
;
Qiu, Shi
;
Hou, Jinjun
;
Wu, Wanying
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Lipidomics
Ultrahigh performance supercritical fluid chromatography
Ion mobility spectroscopy
Collision cross section
Panax
Quality control
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer
期刊论文
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:
Liu, Xue-ling
;
Xu, Yi-chao
;
Wang, Yu-xiang
;
Chen, Yi
;
Wang, Bo-bo
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  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
PIK3CA
HER2
Akt
Patient-derived xenograft (PDX)
Structural studies and drug discovery of G protein-coupled receptors
期刊论文
Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1362-1373
作者:
Yang Zhenlin
;
Wu Beili
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  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
G protein-coupled receptor
drug target
3D structure
ligand
structure-based drug discovery
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
EZH2
Epigenetics
PRC2
Computational drug design
Pharmacophore-based virtual screening
Selective and comprehensive characterization of the quinochalcone C-glycoside homologs in Carthamus tinctorius L. by offline comprehensive two-dimensional liquid chromatography/LTQ-Orbitrap MS coupled with versatile data mining strategies
期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 1, 页码: 495-506
作者:
Yang, Wenzhi
;
Si, Wei
;
Zhang, Jingxian
;
Yang, Min
;
Pan, Huiqin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Separation and characterization of phenolic compounds and triterpenoid saponins in licorice (Glycyrrhiza uralensis) using mobile phase-dependent reversed-phase x reversed-phase comprehensive two-dimensional liquid chromatography coupled with mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2015, 卷号: 1402, 页码: 36-45
作者:
Qiao, Xue
;
Song, Wei
;
Ji, Shuai
;
Wang, Qi
;
Guo, De-an
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
2DLC
Licorice
Glycyrrhiza uralensis
Phenolic compounds
Triterpenoid saponins
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