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科研机构
上海药物研究所 [61]
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期刊论文 [60]
会议论文 [1]
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2021 [4]
2020 [1]
2019 [9]
2018 [7]
2017 [4]
2016 [3]
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Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 181, 页码: 6
作者:
Hu, Shuwei
;
Chen, Xiaoyu
;
Zhu, Mengying
;
Hu, Huifang
;
Zhou, Chen
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
Deubiquitinase
USP20
DUSP domain
NMR
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhang, Wan-ting
;
Liu, Ting-ting
;
Wu, Man
;
Chen, Xiao-chen
;
Han, Li
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
nanobody
FGL1
cancer immunology
diagnosis
immune checkpoint
Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis
期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2020, 卷号: 12, 期号: 4, 页码: 277-290
作者:
Zhao, Mingxia
;
Shen, Lihong
;
Ouyang, Zijun
;
Li, Manru
;
Deng, Guoliang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
hnRNP A1
insulin resistance
hepatic steatosis
glycogen synthesis
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG-Templated Self-Assembly of Paclitaxel Nanoparticles
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2019, 页码: 13
作者:
Feng, Bing
;
Niu, Zifei
;
Hou, Bo
;
Zhou, Lei
;
Li, Yaping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
immune checkpoint blockade
immunogenic cell death
immunotherapy
self-assemble
triple negative breast cancer
DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism
期刊论文
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 期号: 1, 页码: 22
作者:
Chen, Ling
;
Shi, Ying
;
Liu, Na
;
Wang, Zuli
;
Yang, Rui
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
LSH
P53
DUB
PKM2
Lipid metabolism
One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 91, 页码: 8
作者:
Zhao, Kai
;
Tang, Feng
;
Shi, Wei
;
Hong, Haofei
;
Zhou, Zhifang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Endoglycosidase
Cellulose binding domain (CBD)
Cellulose
Immobilization
Antibody glycan remodeling
Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663
作者:
Hu, Jianping
;
Tian, Chang-Qing
;
Damaneh, Mohammadali Soleimani
;
Li, Yanlian
;
Cao, Danyan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC
期刊论文
AUTOPHAGY, 2019, 页码: 15
作者:
Zhang, Sulin
;
Yang, Zhiwen
;
Bao, Weilian
;
Liu, Lixin
;
You, Yan
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/07/01
Colorectal cancer
macroautophagy
SNX10
SRC
tumor growth
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