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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载:22/0  |  提交时间:2022/01/04
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui
收藏  |  浏览/下载:43/0  |  提交时间:2021/11/04
Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver & ndash;alpha-cell axis 期刊论文
BIOSCIENCE REPORTS, 2021, 卷号: 41, 期号: 6, 页码: 12
作者:  Liu, Qiaofeng;  Lin, Guangyao;  Chen, Yan;  Feng, Wenbo;  Xu, Yingna
收藏  |  浏览/下载:26/0  |  提交时间:2021/11/16
Single site Fe on the (110) surface of gamma-Al2O3: insights from a DFT study including the periodic boundary approach 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 卷号: 23, 期号: 12, 页码: 7164-7177
作者:  Gu, Jiande;  Wang, Jing;  Leszczynski, Jerzy
收藏  |  浏览/下载:46/0  |  提交时间:2021/05/24
Glucose-Binding of Periplasmic Protein GltB Activates GtrS-GltR Two-Component System in Pseudomonas aeruginosa 期刊论文
MICROORGANISMS, 2021, 卷号: 9, 期号: 2, 页码: 28
作者:  Xu, Chenchen;  Cao, Qiao;  Lan, Lefu
收藏  |  浏览/下载:110/0  |  提交时间:2021/05/24
Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 12, 页码: 6242-6250
作者:  Abula, Amina;  Xu, Zhijian;  Zhu, Zhengdan;  Peng, Cheng;  Chen, Zhaoqiang
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Synthesis of Axially Chiral Olefin-Oxazoline Ligands via Pd-Catalyzed Multiple C-H Functionalization 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 23, 页码: 9169-9173
作者:  Li, Ling-Jun;  Chen, Jun-Jie;  Feng, Chen-Fei;  Li, Han-Yuan;  Wang, Xing
收藏  |  浏览/下载:7/0  |  提交时间:2021/05/24
The impact of structural modification of sulfated polysaccharides on bone morphogenic protein 2 and inhibition of endothelial cell angiogenesis 期刊论文
CARBOHYDRATE RESEARCH, 2020, 卷号: 496, 页码: 10
作者:  Wang, Ying;  Xiao, Fei;  Jin, Can;  Wang, Wucheng;  Chen, Xia
收藏  |  浏览/下载:17/0  |  提交时间:2020/12/21
Single Fe Site on the Surface of gamma-Al2O3: Insights from Density Functional Theory Periodic Boundary Approach 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY C, 2020, 卷号: 124, 期号: 38, 页码: 20931-20941
作者:  Gu, Jiande;  Wang, Jing;  Leszczynski, Jerzy
收藏  |  浏览/下载:18/0  |  提交时间:2020/12/21
Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459
作者:  Liu Na;  Guo Siqi;  Liu Junfang;  Chen Yantao;  Xu Xiaoming
收藏  |  浏览/下载:21/0  |  提交时间:2020/12/24


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