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Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018, 卷号: 1863, 期号: 8, 页码: 806-822
作者:  Zhao, Zhen-Wang;  Zhang, Min;  Chen, Ling-Yan;  Cong, Duo;  Xia, Xiao-Dan
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
Involvement of microRNAs-MMPs-E-cadherin in the migration and invasion of gastric cancer cells infected with Helicobacter pylori 期刊论文
Experimental Cell Research, 2018, 卷号: 367, 期号: 2, 页码: 196-204
作者:  Yang, Yongmei;  Li, Xiaohui;  Du, Jie;  Yin, Youcong;  Li, Yuanjian*
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/27
Transient receptor potential vanilloid-type 2 targeting on stemness in liver cancer 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 105, 页码: 697-706
作者:  Hu, Zecheng;  Cao, Xiaocheng;  Fang, Yu;  Liu, Guoxing;  Xie, Chengzhi
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/27
HHC  Human Hepatocellular Carcinoma  LCSLC  sliver cancer stem-like cells  TRPV2  Transient Receptor Potential Vanilloid-type 2 channel  TRP  Transient Receptor Potential  SCID  severe combined immunodeficiency  ALDH1  aldehyde dehydrogenase 1  GFP  green fluorescent protein  LPL  lysophospholipids  CAPE  caffeic acid phenethyl ester  hrbFGF  human recombinant basic fibroblast growth factor  hrEGF  human recombinant epidermal growth factor  TRPC  Transient Receptor Potential Canonical  TRPM  Transient Receptor Potential Melastatin  TRPV  Transient Receptor Potential Vanilloid  JNK1  c-jun N-terminal kinase-1  MRP  multidrug-resistant protein  ABCC2  ATP-binding cassette subfamily C member 2  MRP4  Multidrug Resistance Protein 4  CSC  Cancer Stem Cell  DMEM  Dulbecco modified Eagle medium  Liver cancer  Liver cancer stem cell  Transient receptor potential vanilloid-type 2 channel  Probenecid  Tranilast  Self-renewal  
Myocardin: A novel player in atherosclerosis 期刊论文
Atherosclerosis, 2017, 卷号: 257, 页码: 266-278
作者:  Xia, Xiao-Dan;  Zhou, Zhen;  Yu, Xiao-Hua;  Zheng, Xi-Long;  Tang, Chao-Ke*
收藏  |  浏览/下载:26/0  |  提交时间:2019/12/27
Myocardin  Atherosclerosis  Inflammation  Lipid metabolism  VSMC  Abca1  MYOCD  Myocardin  AS  atherosclerosis  SRF  serum response factor  VSMC  vascular smooth muscle cell  Mrtf-A/B  Myocardin-related transcription factors A/B  Mamstr  Mef2-activating SAP transcriptional protein  SAP domain  scaffold attachment factors A and B (SAF-A and -B), Acinus, and PIAS  MADS  MCM1, Agamous, Deficiens, SRF-box transcription factor  TAD  transactivation domain  NTD  N-terminal domain  Arp5  actin-related protein 5  Tead  TEA domain transcription factor  Foxo  forkhead transcription factor  Cdc7  cell division cycle 7  Mef2  myocyte-specific enhancer factor  Nfatc3  nuclear factor of activated T cells c3  hnRNPA1  heterogeneous nuclear ribonucleoprotein A1  Tet2  ten-eleven translocation-2  TGF-β  transforming growth factor-β  URR  upstream repressor region  Klf4  Kruppel-like factor4  PRR  platelet-derived growth factor-BB-responsive region  Pkcα  protein kinase C α  MSCs  mesenchymal stem cells  lncRNAs  long non-coding RNAs  MicroRNAs  small non-encoding RNAs  UTR  un-translated region  Abca1  ATP-binding cassette transporter A1  RCT  reverse cholesterol transport  
PRMT2β, a C-terminal splice variant of PRMT2, inhibits the growth of breast cancer cells 期刊论文
Oncology Reports, 2017, 卷号: 38, 期号: 2, 页码: 1303-1311
作者:  Zhong, Jing;  Chen, Ya-Jun;  Chen, Ling;  Shen, Ying-Ying;  Zhang, Qing-Hai
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27
Steroid receptor RNA activator: Biologic function and role in disease 期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:  Liu, Chan;  Wu, Hong-Tao;  Zhu, Neng;  Shi, Ya-Ning;  Liu, Zheng
收藏  |  浏览/下载:61/0  |  提交时间:2019/12/27
AF-2  activation function-2  AR  androgen receptor  C/EBPα  ccaat-enhancer-binding protein α  CTCF  CCCTC-binding factor  Ddx5  DEAD box protein 5  ERα  estrogen receptor α  GR  glucocorticoid receptor  Hes1  hairy and enhancer of split-1  HP1γ  heterochromatin protein 1γ  JNK  c-Jun N-terminal kinases  lncRNA  long noncoding RNA  MyoD  myogenic differentiation 1  NANOG  homeobox protein NANOG  NR  nuclear receptor(s)  p38 MAPK  mitogen-activated protein kinase  PACT  protein kinase RNA activator  PCOS  polycystic ovary syndrome  PKR  protein kinase RNA-dependent  PPARγ  Peroxisome Proliferator-Activated Receptor gamma  PR  progesterone receptor  PRC2  polycomb repressive complex 2  preTCRα  pre T-cell antigen receptor alpha  Pus1p  pseudouridine synthesis protein  RAR  retinoic acid receptor  RBP-J  recombination signal-binding protein J  RRM  RNA recognition motif  SF-1  steroidogenic factor 1  SHARP  retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein  SLIRP  stem-loop loop-interacting RNA RNA-binding protein  SRA  Steroid receptor RNA activator  SRAP  steroid receptor RNA activator protein  SRC-1  steroid receptor coactivator-1  STR  stem-loop structure  TNFα  tumor necrosis factor α  TRBP  transactivation response RNA-binding protein  TrxG  trithorax group  SRA  Long noncoding RNAs  Nuclear receptor  Transcriptional coactivator  
Autophagy: A double-edged sword in intervertebral disk degeneration 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2016, 卷号: 457, 页码: 27-35
作者:  Zhang, Shu-Jun;  Yang, Wei;  Wang, Cheng;  He, Wen-Si;  Deng, Hai-Yang
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/27
IVD  intervertebral disk  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  ECM  extracellular matrix  Col II  type II collagen  Col I  type I collagen  IDD  intervertebral disk degeneration  LBP  low back pain  miRNAs  microRNAs  ADAMTS  a disintegrin and metalloprotease with thrombospondin motif  MMP  matrix metalloproteinases  HSC70  heat shock cognate protein of 70 kDa  LAMP2A  lysosome-associated membrane protein type-2 A  Atg  autophagy-related genes  ULK  uncoordinated-51-like kinase  PI3KCIII  class III phosphatidylinositol 3-kinase  mTORC1  mammalian target of rapamycin complex 1  DFCP1  double FYVE-containing protein 1  3-MA  3-methyladenine  LC3  microtubule-associated protein 1 light chain 3  PE  phosphatidyl ethanolamine  LAMP-2  lysosomal membrane protein 2  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  NF-κB  nuclear factor-κB  JNK  c-Jun N-terminal kinase  SIRT1  silent mating type information regulator 2 homolog 1  TGF-β1  transforming growth factor-β1  ERK1/2  extracellular signal-regulated kinase 1/2  GRP78  glucose regulated protein 78  H2O2  hydrogen peroxide  Autophagy  IVD  IDD  NP  AF  
Identification of the C-terminal domain of Daxx acts as a potential regulator of intracellular cholesterol synthesis in HepG2 cells 期刊论文
Biochemical and Biophysical Research Communications, 2016, 卷号: 480, 期号: 1, 页码: 139-145
作者:  Sun, Shaowei;  Wen, Juan;  Qiu, Fei;  Yin, Yufang;  Xu, Guina
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
Interleukin-1β in intervertebral disk degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:  Yang, Wei;  Yu, Xiao-Hua;  Wang, Cheng;  He, Wen-Si;  Zhang, Shu-Jun
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
IDD  intervertebral disk degeneration  IL-1  interleukin-1  IVD  intervertebral disk  ECM  extracellular matrix  LBP  low back pain  MMPs  matrix metalloproteinases  NP  nucleus pulposus  AF  annulus fibrosus  Col II  type II collagen  Col I  type I collagen  NTP  N-terminal peptide  NLS  nuclear localization sequence  IL-1RII  IL-1 receptor type II  TLRs  Toll-like receptors  IL-1RI  IL-1 receptor type I  IL-1RAcP  IL-1 receptor accessory protein  TIR  Toll-like/IL-1 receptor  MyD88  myeloid differentiation factor 88  TNF  tumor necrosis factor  NF-κB  nuclear factor-kappa B  MAPK  mitogen-activated protein kinase  IL-1Ra  IL-1 receptor antagonist  IFN-γ  interferon-γ  CCL  CC chemokine ligand  CXCL  CX chemokine ligand  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  TIMPs  tissues inhibitors of metalloproteinases  VEGF  vascular endothelial growth factor  NGF  nerve growth factor  BDNF  brain-derived neurotrophic factor  ROS  reactive oxygen species  SOD  superoxide dismutase  CAT  catalase  miRNAs  microRNAs  MSCs  mesenchymal stem cells  PRP  platelet-rich plasma  IL-1  IDD  Inflammatory responses  Angiogenesis  Apoptosis  
Interleukin-1β in intervertebral disk degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:  WeiYang;  Xiao-HuaYu;  ChengWang;  Wen-SiHe;  Shu-JunZhang
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/27
IDD  intervertebral disk degeneration  IL-1  interleukin-1  IVD  intervertebral disk  ECM  extracellular matrix  LBP  low back pain  MMPs  matrix metalloproteinases  NP  nucleus pulposus  AF  annulus fibrosus  Col II  type II collagen  Col I  type I collagen  NTP  N-terminal peptide  NLS  nuclear localization sequence  IL-1RII  IL-1 receptor type II  TLRs  Toll-like receptors  IL-1RI  IL-1 receptor type I  IL-1RAcP  IL-1 receptor accessory protein  TIR  Toll-like/IL-1 receptor  MyD88  myeloid differentiation factor 88  TNF  tumor necrosis factor  NF-κB  nuclear factor-kappa B  MAPK  mitogen-activated protein kinase  IL-1Ra  IL-1 receptor antagonist  IFN-γ  interferon-γ  CCL  CC chemokine ligand  CXCL  CX chemokine ligand  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  TIMPs  tissues inhibitors of metalloproteinases  VEGF  vascular endothelial growth factor  NGF  nerve growth factor  BDNF  brain-derived neurotrophic factor  ROS  reactive oxygen species  SOD  superoxide dismutase  CAT  catalase  miRNAs  microRNAs  MSCs  mesenchymal stem cells  PRP  platelet-rich plasma  IL-1  IDD  Inflammatory responses  Angiogenesis  Apoptosis  


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