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浏览/检索结果: 共20条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305 作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang 收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 allosteric inhibitor  HIV-1 protease  MM-GBSA  normal mode analysis  REMD   Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells 期刊论文 JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 11, 页码: 1064-1074 作者:  Yang, Qian-Hao;  Jiang, Cheng-Shi;  Jin, Tao;  Xu, Jin-Fang;  Qu, Ting-Li 收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01 Tetrandrine derivatives  non-small cell lung carcinoma  NSCLC A549 cells  anticancer activities  Suzuki-Miyaura reaction   A 20(S)-protopanaxadiol derivative PPD12 reverses ABCB1-mediated multidrug resistance with oral bioavailability and low toxicity 期刊论文 ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 5, 页码: 5891-5899 作者:  Wei, Shunfeng;  Chen, Wantao;  Hu, Lihong;  Pan, Jinsong;  Wang, Xu 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 multidrug resistance  ATP-binding cassette subfamily B member 1  toxicity  pharmacokinetics   A new class of HIV-1 inhibitors and the target identification via proteomic profiling 期刊论文 SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 1430-1439 作者:  Ge, Ying-Zi;  Zhou, Bin;  Xiao, Ruo-Xuan;  Yuan, Xiao-Jing;  Zhou, Hu 收藏  |  浏览/下载：185/0  |  提交时间：2019/01/08 ergostane-type steroids  anti-HIV  target identification  PKM2   Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503 作者:  Dong, Jiajia;  Olaleye, Olajide E.;  Jiang, Rongrong;  Li, Jing;  Lu, Chuang 收藏  |  浏览/下载：101/0  |  提交时间：2019/01/08 New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264 作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Tanshinone-1  S222  S439  Anticancer targets  DNA topoisomerases  P53   Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities 期刊论文 FITOTERAPIA, 2018, 卷号: 128, 页码: 102-111 作者:  Li, Jun;  Li, Hui-hui;  Wang, Wen-qiong;  Song, Wei-bin;  Wang, Yi-ping 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 Euphorbia helioscopia  Jatrophanes  Hyperlipidemia  Lipid-lowering  LDL receptor   Jatrophanes as promising multidrug resistance modulators: Advances of structure-activity relationships 期刊论文 FITOTERAPIA, 2018, 卷号: 127, 页码: 138-145 作者:  Li, Jun;  Wang, Wen-qiong;  Tang, Shuai;  Song, Wei-bin;  Xuan, Li-jiang 收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 Euphorbia helioscopia  Multidrug resistance  Jatrophanes   Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor alpha Activation 期刊论文 MOLECULAR PHARMACOLOGY, 2018, 卷号: 93, 期号: 6, 页码: 563-574 作者:  Wang, Le;  Ma, Leilei;  Lin, Yunfei;  Liu, Xing;  Xiao, Ling 收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 5, 页码: 502-506 作者:  Guo, Yalan;  Wang, Yujie;  Li, Haihong;  Wang, Ke;  Wan, Qi 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Phenylsulfonylfuroxan  3-benzyl coumarin  anticancer  multidrug resistance  P-gp overexpression