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浏览/检索结果: 共23条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文 FRONTIERS IN CHEMISTRY, 2017, 卷号: 5 作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia 收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 EGFR  tyrosine kinase inhibitors  anilinopyrtmidine  glycosides  carbohydrate-based drugs   Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Epidermal growth factor receptor  Tyrosine kinase inhibitors  Non-small cell lung cancer  T790M  Mutant-selective   Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Regulating cancer associated fibroblasts with losartan-loaded injectable peptide hydrogel to potentiate chemotherapy in inhibiting growth and lung metastasis of triple negative breast cancer 期刊论文 BIOMATERIALS, 2017, 卷号: 144, 页码: 60-72 作者:  Hu, Chunhua;  Liu, Xiaoyu;  Ran, Wei;  Meng, Jia;  Zhai, Yihui 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Self-assembly  Hydrogel  Cancer associated fibroblasts  Metastasis  Triple negative breast cancer   Solid-State Characterization and Insight into Transformations and Stability of Apatinib Mesylate Solvates 期刊论文 CRYSTAL GROWTH & DESIGN, 2017, 卷号: 17, 期号: 11, 页码: 5994-6005 作者:  Zhu, Bin;  Zhang, Qi;  Ren, Guobin;  Mei, Xuefeng 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase 期刊论文 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278 作者:  Dai, Xiaoyang;  Yan, Juan;  Fu, Xuhong;  Pan, Qiuming;  Sun, Danni 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Optimization of 1H-indazol-3-amine derivatives as potent fibroblast growth factor receptor inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 16, 页码: 3782-3786 作者:  Cui, Jing;  Peng, Xia;  Gao, Dingding;  Dai, Yang;  Ai, Jing 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 FGFR  Inhibitors  Cellular activity  Fluorine   Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 8, 页码: 830-834 作者:  Lu, Dong;  Yan, Juan;  Wang, Lang;  Liu, Hongchun;  Zeng, Limin 收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 Dual c-Met/HDAC inhibitor  hybrid  designed multiple ligand (DML)   Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6018-6035 作者:  Zhu, Wei;  Chen, Hui;  Wang, Yulan;  Wang, Jiang;  Peng, Xia 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08