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浏览/检索结果: 共89条，第1-10条 帮助 限定条件 发表日期：2016    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 24, 页码: 11050-11068 作者:  Liu, Gang;  Xue, Ding;  Yang, Jun;  Wan, Juan;  Liu, Xiaohua 收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis 期刊论文 CELL RESEARCH, 2016, 卷号: 26, 期号: 12, 页码: 1330-1344 作者:  Zhang, Lin;  Xiao, Jianfeng;  Xu, Jianrong;  Fu, Tianran;  Cao, Zhiwei 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 fatty acid biosynthesis  dehydratase  ACP  complex structure   Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 12, 页码: 1587-1596 作者:  Wang, Yue-qin;  Shen, Ai-jun;  Sun, Jing-ya;  Wang, Xin;  Liu, Hong-chun 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 non-small cell lung cancer  gefitinib resistance  Hsp90   Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II 期刊论文 LIFE SCIENCES, 2016, 卷号: 166, 页码: 75-81 作者:  Wu, Peng;  Han, Na;  Yua, Haitao;  Wang, Linlin;  Li, Xue 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Salvianolic acid C  Aortic aneurysm  Matrix metalloproteinase   Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for Ovarian Cancer 期刊论文 EBIOMEDICINE, 2016, 卷号: 14, 页码: 44-54 作者:  Li, Xiaoguang;  Zhou, Yu;  Liu, Yanling;  Zhang, Xu;  Chen, Tao 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Dihydroartemisinin  Drug conjugates  Cell cycle  Apoptosis  Metastasis  Ovarian cancer   Optimized synthesis and crystalline stability of gamma-cyclodextrin metal-organic frameworks for drug adsorption 期刊论文 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2016, 卷号: 514, 期号: 1, 页码: 212-219 作者:  Liu, Botao;  Li, Haiyan;  Xu, Xiaonan;  Li, Xue;  Lv, Nana 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Cyclodextrin-metal-organic frameworks  Synthesis  Crystalline stability  Drug adsorption   Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy 期刊论文 ACS APPLIED MATERIALS & INTERFACES, 2016, 卷号: 8, 期号: 47, 页码: 32159-32169 作者:  Cui, Yanna;  Zhang, Meng;  Zeng, Feng;  Jin, Hongyue;  Xu, Qin 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 brain targeting delivery  magnetic targeting  PLGA nanoparticles  paclitaxel  curcumin  T7 peptide   CXCR4 ACTIVATION PROMOTES DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS TO NEURAL STEM CELLS 期刊论文 NEUROSCIENCE, 2016, 卷号: 337, 页码: 88-97 作者:  Zhang, Lijun;  Hua, Qiuhong;  Tang, Kaiyi;  Shi, Changjie;  Xie, Xin 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 human embryonic stem cell  neural stem/precursor cell  neural differentiation  chemokine receptor  CXCR4  SDF-1   Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors 期刊论文 ADVANCED MATERIALS, 2016, 卷号: 28, 期号: 43, 页码: 9581-+ 作者:  Sun, Huiping;  Su, Jinghan;  Meng, Qingshuo;  Yin, Qi;  Chen, Lingli 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5399-5402 作者:  Han, Mei;  Wang, Chengyan;  Ji, Yinchun;  Song, Zilan;  Xing, Li 收藏  |  浏览/下载：66/0  |  提交时间：2019/01/08 EML4-ALK kinase  Oxidative metabolism  Benzo[b]carbazolone  hERG  Antitumor activity