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Labile, recalcitrant, microbial carbon and nitrogen and the microbial community composition at two Abies faxoniana forest elevations under elevated temperatures 期刊论文
SOIL BIOLOGY & BIOCHEMISTRY, 2015, 卷号: 91, 页码: 1-13
作者:  Xu, Gang;  Chen, Juan;  Berninger, Frank;  Pumpanen, Jukka;  Bai, Jingwen
收藏  |  浏览/下载：38/0  |  提交时间：2015/12/21
Suppression of casein kinase 2 sensitizes tumor cells to antitumor TRAIL therapy by regulating the phosphorylation and localization of p65 in prostate cancer 期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 3
作者:  Gang, Xiaokun;  Wang, Yao;  Wang, Yingdi;  Zhao, Yu;  Ding, Liya
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/05
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension 期刊论文
HUMAN MOLECULAR GENETICS, 2015, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 865-874
作者:  Lu, Xiangfeng;  Wang, Laiyuan;  Lin, Xu;  Huang, Jianfeng;  Gu, C. Charles
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/02
Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling 期刊论文
Drug Design, Development and Therapy, 2015, 卷号: 9, 页码: 2139-2148
作者:  Zhang, Lei;  Xu, Xuan;  Yang, Ruhao;  Chen, Jingwen;  Wang, Shixuan
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
Recent studies have demonstrated that paclitaxel might inhibit renal fibrosis. However  the underlying molecular mechanism remains unclear. In this study  we hypothesized that low-dose paclitaxel may block the STAT3 (signal transducer and activator of transcription 3) signaling to attenuate fibrosis in a mouse model with unilateral ureteral obstruction. Both NRK-49F cells and mice with unilateral ureteral obstruction were treated with paclitaxel. The results showed that paclitaxel treatment resulted in a dose- and time-dependent decrease in tyrosine-phosphorylated STAT3  and inhibited the expression of fibronectin  alpha-smooth muscle actin (α-SMA)  and collagen I in cultured NRK-49F cells. S3I-201  an STAT3 inhibitor  also suppressed the expression of fibronectin  α-SMA  and collagen I in cultured NRK-49F cells. Mechanistically  paclitaxel treatment blocked the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation. Furthermore  paclitaxel also ameliorated renal fibrosis by down-regulating the expression of fibronectin  α-SMA  and collagen I  and suppressed the infiltration of macrophages and production of TNF-α  IL-1β  TGF-β  and ICAM-1 (intercellular adhesion molecule 1) by inhibition of STAT3 activity in obstructive nephropathy. These results suggest that paclitaxel may block the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation  consequently leading to the suppression of renal interstitial fibroblast activation and the development of renal fibrosis  and inhibition of proinflammatory cytokine production.  
CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation membrane 期刊论文
NATURE CELL BIOLOGY, 2015
Mi, Na; Chen, Yang; Wang, Shuai; Chen, Mengran; Zhao, Mingkun; Yang, Guang; Ma, Meisheng; Su, Qian; Luo, Sai; Shi, Jingwen; Xu, Jia; Guo, Qiang; Gao, Ning; Sun, Yujie; Chen, Zhucheng; Yu, Li
收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03
Molecular markers for identifying a new selected variety of Pacific white shrimp Litopenaeus vannamei 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 1, 页码: 1-10
作者:  Yu Yang;  Zhang Xiaojun;  Liu Jingwen;  Li Fuhua;  Huang Hao
收藏  |  浏览/下载：13/0  |  提交时间：2015/06/15
无权访问的条目 期刊论文
作者:  Lu, Xiangfeng;  Wang, Laiyuan;  Lin, Xu（林旭）;  Huang, Jianfeng;  Gu, C. Charles
收藏  |  浏览/下载：65/0  |  提交时间：2015/09/24
房价高增长与企业“低技术锁定”———基于中国工业企业数据库的微观证据 期刊论文
上海财经大学学报, 2015, 卷号: 17, 页码: 44-56
作者:  余静文[1];  王媛[2];  谭静[3]
收藏  |  浏览/下载：1/0  |  提交时间：2019/04/26
房价、流动性效应与企业融资约束 期刊论文
产业经济研究, 2015, 页码: 91-101
作者:  余静文[1];  谭静[2]
收藏  |  浏览/下载：1/0  |  提交时间：2019/04/30
Phenyliodine(III) Diacetate Mediated Oxidative Cyclization of 1-Alkenoyl-1-carbamoyl Cycloalkanes: Access to Spiro-Fused Dihydrofuran-3(2H)-ones 期刊论文
organic letters, 2015, 卷号: 17, 期号: 20, 页码: 5012-5015
作者:  Yuan,Jingwen;  Zhang,Qian;  Yu,Mangfei;  Huang,Peng;  Zhang,Rui
收藏  |  浏览/下载：14/0  |  提交时间：2016/05/04

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