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科研机构
中国医学科学院 北京... [6]
山东大学 [2]
内容类型
期刊论文 [8]
发表日期
2018 [8]
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APPLICATION OF MILD HYPOTHERMIA THERAPY COMBINED WITH 3-N-BUTYLPHTHALIDE IN TREATMENT OF RATS WITH CEREBRAL ISCHEMIA-REPERFUSION INJURY
期刊论文
ACTA MEDICA MEDITERRANEA, 2018, 卷号: 34, 期号: 6, 页码: 1959-1965
作者:
Xie, Kun
;
Yu, Jingui
;
Sun, Guoyong
;
Li, Chuangang
;
Wang, Hui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
mild hypothermia
n-Butylphthalide
cerebral ischemia-reperfilsion
injury
neuroprotection
mTOR
L-3-n-butylphthalide may attenuate A beta(1-42)-induced neuronal apoptosis and synaptotoxicity in primary cultured cortical neurons possibly via modulating both PI3K/AKT and ERK signaling pathways
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 卷号: 11, 期号: 9, 页码: 9167-9177
作者:
Zhao, Yunxia
;
Zhang, Yong
;
Chen, Xiuying
;
Dong, Wei
;
Du, Yifeng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
Alzheimer's disease (AD)
beta-amyloid (A beta)
apoptosis
PI3K/AKT
pathway
ERK pathway
Protective Effects of L-3-n-Butylphthalide Against H2O2-Induced Injury in Neural Stem Cells by Activation of PI3K/Akt and Mash1 Pathway
期刊论文
2018, 卷号: 393, 页码: 164-174
作者:
Wang, Shan
;
Huang, Longjian
;
Zhang, Yong
;
Peng, Yuchen
;
Wang, Xiaoliang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
neural stem cells
L-3-n-butylphthalide
oxidative stress
neurogenesis
Mash1
From stroke to neurodegenerative diseases: The multi-target neuroprotective effects of 3-n-butylphthalide and its derivatives
期刊论文
2018, 卷号: 135, 页码: 201-211
作者:
Huang, Longjian
;
Wang, Shan
;
Ma, Fei
;
Zhang, Yong
;
Peng, Yuchen
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
3-n-Butylphthalide
Stroke
Neurodegenerative disease
Multi-target
Drug repositioning
Dl-3-n-Butylphthalide (NBP): A Promising Therapeutic Agent for Ischemic Stroke
期刊论文
2018, 卷号: 17, 期号: 5, 页码: 338-347
作者:
Wang, Shan
;
Ma, Fei
;
Huang, Longjian
;
Zhang, Yong
;
Peng, Yuchen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Dl-3-n-butylphthalide
ischemic stroke
cerebral microcirculation
neuroprotection
mitochondria
apoptosis
oxidative stress
L-3-n-Butylphthalide Regulates Proliferation, Migration, and Differentiation of Neural Stem Cell In Vitro and Promotes Neurogenesis in APP/PS1 Mouse Model by Regulating BDNF/TrkB/CREB/Akt Pathway
期刊论文
2018, 卷号: 34, 期号: 3, 页码: 477-488
作者:
Lei, Hui
;
Zhang, Yu
;
Huang, Longjian
;
Xu, Shaofeng
;
Li, Jiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Alzheimer's disease
L-3-n-Butylphthalide
Neural stem cells
Neurogenesis
BDNF
CREB
Akt
DL-3-n-Butylphthalide reduces atrial fibrillation susceptibility by inhibiting atrial structural remodeling in rats with heart failure
期刊论文
2018, 卷号: 391, 期号: 3, 页码: 323-334
作者:
Qiu, Huiliang
;
Wu, Huanlin
;
Ma, Jin
;
Cao, Haiming
;
Huang, Lihua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
DL-3-n-Butylphthalide
Atrial structural remodeling
Heart failure
Atrial fibrillation
Conversion and pharmacokinetics profiles of a novel pro-drug of 3-n-butylphthalide, potassium 2-(1-hydroxypentyl)-benzoate, in rats and dogs
期刊论文
2018, 卷号: 39, 期号: 2, 页码: 275-285
作者:
Li, Jiang
;
Xu, Shao-feng
;
Peng, Ying
;
Feng, Nan
;
Wang, Ling
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/01/03
potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB)
pro-drug
3-n-butylphthalide (dl-NBP)
ischemic stroke
pharmacokinetics
bioavailability
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