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上海药物研究所 [3]
西安交通大学 [1]
江苏大学 [1]
中南大学 [1]
暨南大学 [1]
吉林大学白求恩第一医... [1]
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期刊论文 [8]
发表日期
2017 [8]
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Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:
Zhang, Wei-yao
;
Lu, Wen-chao
;
Jiang, Hao
;
Lv, Zheng-bing
;
Xie, Yi-qian
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
epigenetics
molecular docking
PRMT1
scaffold hopping
small-molecule inhibitor
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
作者:
Wang, Chen
;
Jiang, Hao
;
Jin, Jia
;
Xie, Yiqian
;
Chen, Zhifeng
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2019/01/08
Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 17, 页码: 3648-3661
作者:
Ye, Yan
;
Zhang, Bidong
;
Mao, Ruifeng
;
Zhang, Chenhua
;
Wang, Yulan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Automethylation of protein arginine methyltransferase 7 and its impact on breast cancer progression
期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 6
作者:
Lu, Jun
;
Geng, Pengyu
;
Zhang, Yu
;
Liu, Xiaoqing
;
Zhang, Na
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
migration
invasion
E-cadherin
YY1
Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
期刊论文
2017, 卷号: 36, 期号: [db:dc_citation_issue], 页码: 1223
作者:
Deng, X.[1]
;
Shao, G.[1,2]
;
Zhang, H-T[1,3]
;
Li, C.[4]
;
Zhang, D.[5]
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Critical role of vascular peroxidase 1 in regulating endothelial nitric oxide synthase
期刊论文
Redox Biology, 2017, 卷号: 12, 页码: 226-232
作者:
Liu, Zhaoya
;
Liu, Yanbo
;
Xu, Qian
;
Peng, Haiyang
;
Tang, Yixin
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
DDAH2
dimethylarginine dimethylaminohydrolase2
H2O2
hydrogen peroxide
ADMA
asymmetric Dimethylarginine
HOCl
hypochlorous acid
eNOS
endothelial nitric oxide synthase
PRMT1
Protein arginine methyltransferase1
ROS
reactive oxygen species
NO
nitric oxide
Vascular peroxidase 1
Endothelial nitric oxide synthase
Nitric oxide
Asymmetricdimethylarginine
Angiotensin II
Oxidative stress
Constitutive high expression of protein arginine methyltransferase 1 in asthmatic airway smooth muscle cells is caused by reduced microRNA-19a expression and leads to enhanced remodeling
期刊论文
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 卷号: 140, 页码: 510-+
作者:
Sun, Qingzhu
;
Liu, Li
;
Wang, Hui
;
Mandal, Jyotshna
;
Khan, Petra
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  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
primary airway smooth muscle cell
Airway wall remodeling
STAT1
protein arginine methyltransferase 1
miR-19a
extracellular signal-regulated kinase
Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
期刊论文
ONCOGENE, 2017, 卷号: 36, 期号: 9, 页码: 1223-1231
作者:
Deng, X.[1]
;
Shao, G.[2]
;
Zhang, H-T[3]
;
Li, C.[4]
;
Zhang, D.[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/24
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