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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2013     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 24, 页码: 7988-7998 作者:  Zhang, Xu;  Peng, Ting;  Ji, Xun;  Li, Jian;  Tong, Linjiang 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 EGFR inhibitor  EGFR T790M/L858R  Binding mode  Irreversible EGFR inhibitor   Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting EGFR 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 4, 期号: 10, 页码: 974-978 作者:  Wu, Jianwei;  Chen, Wenteng;  Xia, Guangxin;  Zhang, Jing;  Shao, Jiaan 收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Anticancer  kinase inhibitor  EGFR  conformationally constrained   3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses 期刊论文 JOURNAL OF VIROLOGY, 2013, 卷号: 87, 期号: 8, 页码: 4339-4351 作者:  Tan, Jinzhi;  George, Shyla;  Kusov, Yuri;  Perbandt, Markus;  Anemueller, Stefan 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 20 Zhou, Wei; Liu, Xiaofeng; Tu, Zhengchao; Zhang, Lianwen; Ku, Xin; Bai, Fang; Zhao, Zhenjiang; Xu, Yufang; Ding, Ke; Li, Honglin 收藏  |  浏览/下载：16/0  |  提交时间：2016/12/16 Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 20 作者:  Tu, Zhengchao;  Liu, Xiaofeng;  Ku, Xin;  Bai, Fang;  Zhou, Wei 收藏  |  浏览/下载：14/0  |  提交时间：2018/12/13 Design, Synthesis, and Biological Evaluation of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidinyl Derivatives as New Irreversible Epidermal Growth Factor Receptor Inhibitors with Improved Pharmacokinetic Properties 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 21 作者:  Xu, Tianfeng;  Ding, Ke;  Ren, Xiaomei;  Tu, Zhengchao;  Lu, Xiaoyun 收藏  |  浏览/下载：8/0  |  提交时间：2018/12/13 Design, Synthesis, and Biological Evaluation of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidinyl Derivatives as New Irreversible Epidermal Growth Factor Receptor Inhibitors with Improved Pharmacokinetic Properties 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 21 Xu, Shilin; Xu, Tianfeng; Zhang, Lianwen; Zhang, Zhang; Luo, Jinfeng; Liu, Yingxue; Lu, Xiaoyun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke 收藏  |  浏览/下载：14/0  |  提交时间：2016/12/16 Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 页码: 7821-7837 作者:  Zhou, Wei;  Liu, Xiaofeng;  Tu, Zhengchao;  Zhang, Lianwen;  Ku, Xin 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/11