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Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study
期刊论文
PEERJ, 2018, 卷号: 6
作者:
Hu, Xiao-na
;
Wang, Jiao-feng
;
Huang, Yi-qin
;
Wang, Zheng
;
Dong, Fang-yuan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Huperzine A
Hepatocyte senescence
Nonalcoholic fatty liver disease
Apoptosis
Repeated pre-training sleep restriction in adolescent rats impaired spatial performance
期刊论文
SLEEP AND BIOLOGICAL RHYTHMS, 2017, 卷号: 15, 期号: 1
作者:
Yang, Su-Rong
;
Sun, Huan-Xin
;
Hu, Zhen-Zhen
;
Wang, Si-Heng
;
Sun, Hui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Adolescent rat
Prior repeated sleep restriction
Morris water maze test
Huperzine A
Administration of Huperzine A exerts antidepressant-like activity in a rat model of post-stroke depression
期刊论文
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2017, 卷号: 158, 页码: 32-38
作者:
Du, Yuan
;
Liang, Haiyue
;
Zhang, Leiming
;
Fu, Fenghua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Post-stroke depression
Huperzine A
Neurological function
Cognitive
function
Neurotransmitter
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1391-1400
作者:
Tao, Ling-xue
;
Huang, Xiao-tian
;
Chen, Yu-ting
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
iron
reactive oxygen species
mitochondria dysfunction
acetylcholinesterase
Evaluation of the in vitro and in vivo metabolic pathway and cytochrome P450 inhibition/induction profile of Huperzine A
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 480, 期号: 2
作者:
Lin, Ping-ping
;
Li, Xue-ning
;
Yuan, Fei
;
Chen, Wei-li
;
Yang, Meng-jie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Huperzine A
Metabolic pathway
CYP inhibition
CYP induction
Drug interaction
Huperzine A Alleviates Oxidative Glutamate Toxicity in Hippocampal HT22 Cells via Activating BDNF/TrkB-Dependent PI3K/Akt/mTOR Signaling Pathway
期刊论文
Cellular and Molecular Neurobiology, 2016, 卷号: 36, 期号: 6, 页码: 915-925
作者:
Mao, Xiao-Yuan*
;
Zhou, Hong-Hao
;
Li, Xi
;
Liu, Zhao-Qian*
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/03
Huperzine A
Oxidative glutamate toxicity
HT22 cells
Brain-derived neurotrophic factor
Phosphatidylinositol 3 kinase
Apoptosis
Population pharmacokinetic modeling and simulation of huperzine A in elderly Chinese subjects
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7
作者:
Sheng, Lei
;
Qu, Yi
;
Yan, Jing
;
Liu, Gang-yi
;
Wang, Wei-liang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/06
huperzine A
Alzheimer's disease
elderly Chinese people
population pharmacokinetics
modeling and simulation
NLME
Ultrastructural mitochondria changes in perihematomal brain and neuroprotective effects of Huperzine A after acute intracerebral hemorrhage
期刊论文
NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2015, 卷号: 11
作者:
Lu, Haiying
;
Jiang, Mei
;
Lu, Lei
;
Zheng, Guo
;
Dong, Qiang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
apoptosis
intracerebral hemorrhage
mitochondria
huperzine A
neuroprotection
Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity
期刊论文
MOLECULES, 2014, 卷号: 19, 期号: 7, 页码: 9999-10010
作者:
Zhang, DB
;
Chen, JJ
;
Song, QY
;
Zhang, L
;
Gao, K
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/05/21
Lycopodiastrum casuarinoides
Lycopodiaceae
lycodine alkaloid
acetylcholinesterase
16-hydroxyhuperzine B
N-methyl-11-acetoxyhuperzine B
8,15-dihydrolycoparin A
(7S, 12S, 13R)-huperzine D-16-O-beta-D-glucopyranoside
Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease
期刊论文
NEUROBIOLOGY OF AGING, 2014, 卷号: 35, 期号: 5, 页码: 1045-1054
作者:
Huang, Xiao-Tian
;
Qian, Zhong-Ming
;
He, Xuan
;
Gong, Qi
;
Wu, Ka-Chun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Huperzine A
Alzheimer's disease
Brain iron
Transferrin receptor 1
Double transgenic APPswe/PS1dE9 mice (APP/PS mice)
The neuronal amyloid precursor protein (APP)
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