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Mitochondrial tRNALeu(UUR) C3275T, tRNAGln T4363C and tRNALys A8343G mutations may be associated with PCOS and metabolic syndrome 期刊论文
Gene, 2018, 卷号: 642, 页码: 299-306
作者:  Ding, Yu*;  Xia, Bo-Hou;  Zhang, Cai-Juan;  Zhuo, Guang-Chao
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/27
PCOS  polycystic ovary syndrome  T2DM  type 2 diabetes mellitus  MetS  metabolic syndrome  mtDNA  mitochondrial DNA  TG  triglyceride  HbA1c  Hemoglobin A1c  MMP  mitochondrial membrane potential  ROS  reactive oxygen species  PMNs  polymononuclear leukocytes  IR  insulin resistance  HDL-C  high-density lipoprotein cholesterol  BP  blood pressure  FPG  fast plasma glucose  HPLC  high-pressure liquid chromatography  LH  Luteinizing hormones  TT  total testosterone  FINS  fasting insulin  CI  conservation index  MFE  minimum free energy  PF  partition function  HBSS  Hanks' buffered salt solution  DCFH  2,7-dichlorodihydrofluorescein  BMI  body mass index  LHON  Leber's Hereditary Optic Neuropathy  MetS  PCOS  mt-tRNA mutations  Mitochondrial dysfunction  
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice 期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:  Li, Xiaopeng;  Wu, Qian;  Sui, Yong;  Li, Shuyi;  Xie, Bijun
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/27
A-type procyanidins  Oxidative stress  Glucose homeostasis  Type 2 diabetes  mTOR  ACC1  acetyl coenzyme A carboxylase 1  ACL  ATP-citrate lyase  ALT  alanine aminotransferase  AST  aspartate aminotransferase  AUC  area under curve  BAT  brown adipose tissue  FAS  fatty acid synthase  FFA  free fatty acid  FoxO3a  Forkhead box O3a  FoxO1a  Forkhead box O3a  PKCβ  protein kinase C β  mTOR  mechanistic target of rapamycin  HDL  high-density lipoprotein  GHbA1c  glycated hemoglobin A1c  GK  glucokinase  G-6-Pase  glucose-6-phosphatase  GLP-1  glucagon-like peptide-1  GSH-PX  total glutathione peroxidase  HOMA-IR  homeostatic model assessment of insulin resistance  LDHA  lactate dehydrogenase  LDL  low-density lipoprotein  LPOPC  oligomeric procyanidins of litchi pericarp  MDA  malondialdehyde  MnSOD  manganese superoxide dismutase  mTOR  mechanistic target of rapamycin  OGTT  oral glucose tolerance test  PDH  pyruvate dehydrogenase  PEPCK  phosphoenolpyruvate carboxykinase  PFK  phosphofructokinase  PK  pyruvate kinase  PKCβ  protein kinase C β  PPG  postprandial blood glucose  S6K1  S6 Kinase 1  PKCβ  protein kinase C β  RTK  receptor tyrosine kinase  SREBP-1c  sterol regulatory element-binding protein 1c  ACL  ATP-citrate lyase  ACC1  acetyl coenzyme A carboxylase 1  FAS  fatty acid synthase  SCD1  stearoyl CoA desaturase 1  STZ  streptozotocin  S6K1  S6 kinase 1  PPG  postprandial blood glucose  ROS  reactive oxygen species  TC  total cholesterol  TG  triacylglycerol  STZ  streptozotocin  T-AOC  total antioxidant capacity  T-SOD  total superoxide dismutase  UCP-1  uncoupling protein 1  WAT  white adipose tissue  XOS  xylo-oligosaccharides  
Human fetal intestinal epithelial cells metabolize and incorporate branched chain fatty acids in a structure specific manner 期刊论文
Prostaglandins, leukotrienes, and essential fatty acids, 2017, 卷号: 116, 页码: 32-39
作者:  Liu, Lei;  Wang, Zhen;  Park, Hui Gyu;  Xu, Chuang;  Lawrence, Peter
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/23
miR-467b regulates the cholesterol ester formation via targeting ACAT1 gene in RAW 264.7 macrophages 期刊论文
Biochimie, 2017, 卷号: 132, 期号: Volume 132, 页码: 38-44
作者:  Wang, Bo;  He, Ping-Ping;  Zeng, Gao-Feng;  Zhang, Tao;  Yang, Xin-Ping Ou
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/27
miR-758-5p regulates cholesterol uptake via targeting the CD36 3′UTR 期刊论文
Biochemical and Biophysical Research Communications, 2017, 卷号: 494, 期号: 1-2, 页码: 384-389
作者:  Li, Bi-Rong;  Xia, Lin-Qin;  Liu, Jing;  Liao, Lin-Ling;  Zhang, Yang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27
ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-alpha-processing alteration 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2015, 卷号: 47, 期号: 12
作者:  Zhu, Ming;  Zhao, Xiaonan;  Chen, Jia;  Xu, Jiajia;  Hu, Guangjing
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Association between serum free fatty acid levels and possible related factors in patients with type 2 diabetes mellitus and acute myocardial infarction 期刊论文
BMC CARDIOVASCULAR DISORDERS, 2014, 卷号: 14
作者:  Zhou, Xin
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages 期刊论文
Atherosclerosis, 2014, 卷号: 234, 期号: 1, 页码: 54-64
作者:  Zhang, Min;  Wu, Jian-Feng;  Chen, Wu-Jun;  Tang, Shi-Lin;  Mo, Zhong-Cheng
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27
Foam cells in atherosclerosis 期刊论文
Clinica Chimica Acta, 2013, 卷号: 424, 页码: 245-252
作者:  Yu, Xiao-Hua;  Fu, Yu-Chang;  Zhang, Da-Wei;  Yin, Kai*;  Tang, Chao-Ke
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/27
ABCA1  ABCG1  ACAT1  AGE  ATP-binding cassette transporter A1  ATP-binding cassette transporter G1  Atherosclerosis  CD36  CE  ERK1/2  FC  Foam cells  HDL  LDLR  LXR  MAPK  PI3K  PKB  PKC  PPAR response elements  PPAR-gamma  PPREs  RCT  RXR  SR-A  SR-BI  TGF-beta  acyl coenzyme A:cholesterol acyltransferase-1  advanced glycation end products  apoA-I  apoE  apolipoprotein A-I  apolipoprotein E  cholesterol ester  extracellular signal-regulated kinases 1 and 2  free cholesterol  high-density lipoprotein  liver X receptor  low-density lipoprotein receptor  mitogen-activated protein kinase  nCEH  neutral cholesteryl ester hydrolase  ox-LDL  oxidized low-density lipoprotein  peroxisome proliferator-activated receptor-gamma  phosphatidylinositol 3-kinase  protein kinase B  protein kinase C  retinoid X receptor  reverse cholesterol transport  scavenger receptor BI  scavenger receptor class A  transforming growth factor-beta  
HDL drug carriers for targeted therapy 期刊论文
Clinica Chimica Acta, 2013, 卷号: 415, 页码: 94-100
作者:  Liu, Xing;  Suo, Rong;  Xiong, Sheng-Lin;  Zhang, Qing-Hai;  Yi, Guang-Hui*
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/27


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