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CORC

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Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  
PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment 期刊论文
AUTOPHAGY, 2017
Ma, Ke; Fu, Wan; Tang, Ming; Zhang, Chaohua; Hou, Tianyun; Li, Ran; Lu, Xiaopeng; Wang, Yanan; Zhou, Jingyi; Li, Xue; Zhang, Luyao; Wang, Lina; Zhao, Ying; Zhu, Wei-Guo
收藏  |  浏览/下载：10/0  |  提交时间：2017/12/03
Inhibition of osteopontin reduce the cardiac myofibrosis in dilated cardiomyopathy via focal adhesion kinase mediated signaling pathway 期刊论文
2016, 卷号: 8, 期号: 9, 页码: 3645-3655
作者:  Zhao, Hui;  Wang, Wei;  Zhang, Jie;  Liang, Tuo;  Fan, Guang-Pu
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04
PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism. 期刊论文
Cancer Biology and Therapy, 2015, 卷号: Vol.16 No.2, 页码: 297-306
作者:  Ning Li;  Junfang Qin;  Lan Lan;  Hongyao Zhang;  Fang Liu
收藏  |  浏览/下载：3/0  |  提交时间：2019/02/27
MicroRNAs in osteosarcoma 期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 页码: 9-17
作者:  Zhang, Jian;  Yan, Yi-Guo;  Wang, Cheng;  Zhang, Shu-Jun;  Yu, Xiao-Hua*
收藏  |  浏览/下载：26/0  |  提交时间：2019/12/27
OS  osteosarcoma  miRNAs  microRNAs  CSCs  cancer stem cells  RNA pol  RNA polymerase  DGCR8  DiGeorge syndrome critical gene 8  RISC  RNA-induced silencing complex  Exp 5  exportin 5  Ago  argonaute  MREs  miRNA recognition elements  APE1  apurinic/apyrimidinic endonuclease 1  MDM  murine double minute  TP53  tumor suppressor p53  mTOR  mammalian target of rapamycin  Eag1  ether à go-go 1  PI3K  phosphatidylinositol-3-kinase  PTEN  phosphatase and tensin homolog deleted on chromosome ten  Hsp90B1  heat shock protein 90B1  BMP2  bone morphogenetic protein 2  IGF1R  insulin-like growth factor 1 receptor  FAK  phospho-Akt and focal adhesion kinase  LPAATβ  lysophosphatidic acid acyltransferase β  HMGB1  high-mobility group box 1  FASN  fatty acid synthase  LZTS1  leucine zipper putative tumor suppressor 1  MMP  matrix metalloproteinase  LNA  locked nucleic acid  DATS  diallyl trisulfide  miRNAs  OS  TP53  Notch  Chemoresistance  
The role of integrin-beta/FAK in cyclic mechanical stimulation in MG-63 cells. 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 卷号: 7, 期号: 11, 页码: 7451-7459
作者:  Yang, Min;  Xiao, Li-Wei*;  Liao, Er-Yuan;  Wang, Qiao-Jing;  Wang, Bei-Bei
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
Trans-3,4,5,4 '-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9
作者:  Chen, LK;  Qiang, PF;  Xu, QP;  Zhao, YH;  Dai, F
收藏  |  浏览/下载：3/0  |  提交时间：2014/12/05
Cytoskeletal reorganization mediates fluid shear stress-induced ERK5 activation in osteoblastic cells 期刊论文
CELL BIOLOGY INTERNATIONAL, 2012, 卷号: 36, 期号: 3, 页码: 229-236
作者:  Li, P;  Ma, YC;  Shen, HL;  Han, H;  Wang, J
收藏  |  浏览/下载：5/0  |  提交时间：2016/03/29
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP beta/zeta signaling by menin 期刊论文
http://dx.doi.org/10.1038/onc.2010.282, 2010
Feng, Z-J; Gao, S-B; Wu, Y.; Xu, X-F; Hua, X.; Jin, G-H; 金光辉
收藏  |  浏览/下载：3/0  |  提交时间：2015/07/22
FAAP, a novel murine protein, is involved in cell adhesion through regulating vinculin-paxillin association 期刊论文
frontiers in bioscience landmark, 2008
Hu, Jinsong; Teng, Junlin; Ding, Naizheng; He, Mei; Sun, Yuhui; Yu, Albert Cheung Hoi; Chen, Jianguo
收藏  |  浏览/下载：2/0  |  提交时间：2015/11/16

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