CORC

浏览/检索结果: 共21条,第1-10条 帮助

已选(0)清除 条数/页:   排序方式:
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling
收藏  |  浏览/下载:65/0  |  提交时间:2021/08/17
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 21, 页码: 8653-8663
作者:  Li, Kangshuai;  Hou, Xuben;  Li, Ruirui;  Bi, Wenxiang;  Yang, Fan
收藏  |  浏览/下载:109/0  |  提交时间:2019/12/11
3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578
作者:  Shan Hui;  Yao Sheng;  Ye Yang;  Yu Qiang
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu
收藏  |  浏览/下载:16/0  |  提交时间:2020/12/24
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:59/0  |  提交时间:2019/01/08
Structure Optimization and Structure-Activity Relationship Study of a Kind of Type II FAK Inhibitors with N-Phenylpyrazole Ureas 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 11
作者:  Gong Chaochao;  Tan Hanyi;  Zhang Qian
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05
Inhibition of P-Glycoprotein Mediated Efflux in Caco-2 Cells by Phytic Acid 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 4
作者:  Li, Lujia;  Fu, Qingxue;  Xia, Mengxin;  Xin, Lei;  Shen, Hongyi
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载:72/0  |  提交时间:2016/11/07


©版权所有 ©2017 CSpace - Powered by CSpace