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CORC

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Design, synthesis and biological evaluation of novel, orally bioavailable pyrimidine-fused heterocycles as influenza PB2 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162
作者:  Xiong, Jian;  Wang, Jingjing;  Hu, Guoping;  Zhao, Weili;  Li, Jianqi
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/05
The Crystal Structure of the PB2 Cap-binding Domain of Influenza B Virus Reveals a Novel Cap Recognition Mechanism 期刊论文
the journal of biological chemistry, 2015
Liu Yong; Yang Yongfeng; Fan Jialin; He Ruina; Luo Ming; Zheng Xiaofeng
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/13
Crystallization and X-ray crystallographic analysis of the cap-binding domain of influenza A virus H1N1 polymerase subunit PB2 期刊论文
acta crystallographica section f structural biology and crystallization communications, 2013
Liu, Yong; Meng, Geng; Luo, Ming; Zheng, Xiaofeng
收藏  |  浏览/下载：2/0  |  提交时间：2015/11/11
Multiple amino acid mutations in viral RNA polymerase may synergistically enhance the transmissibility and/or virulence of the 2009 pandemic influenza (H1N1) virus 期刊论文
ACTA VIROLOGICA, 2013, 卷号: 57, 期号: 1
作者:  Wang, X.;  Zhou, S.;  Chen, Y.;  Wei, M.;  Xiong, W.
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/19
Two mutations in the C-terminal domain of influenza virus RNA polymerase PB2 enhance transcription by enhancing cap-1 RNA binding activity 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2012, 卷号: 1819, 期号: 1
作者:  Zhang, Shijian;  Wang, Qiang;  Wang, Jinlan;  Mizumoto, Kiyohisa;  Toyoda, Tetsuya
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/19
Nucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic Center 期刊论文
2010, 2010
Zhao, Cong; Lou, Zhiyong; Guo, Yu; Ma, Ming; Chen, Yutao; Liang, Shuaiyi; Zhang, Liang; Chen, Shoudeng; Li, Xuemei; Liu, Yingfang; Bartlam, Mark; Rao, Zihe
收藏  |  浏览/下载：4/0
基于内含子剪切的人工miRNA结构和靶向位点与基因沉默效率的关系研究 学位论文
2009
作者:  申彦森
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2 期刊论文
VIRUS RESEARCH, 2009, 卷号: 144, 期号: 1-2
作者:  Guo, Deyin
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
H5N1亚型禽流感病毒适应哺乳动物的机制研究 学位论文
2008
作者:  李军伟
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05

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