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科研机构
湖南农业大学 [2]
南华大学 [1]
内容类型
期刊论文 [3]
发表日期
2016 [3]
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DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity
期刊论文
Journal of Hepatology, 2016, 卷号: 65, 期号: 1, 页码: 113-124
作者:
Xie, Lanfeng
;
Wang, Pi-Xiao
;
Zhang, Peng
;
Zhang, Xiao-Jing
;
Zhao, Guang-Nian
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/23
NAFLD
non-alcoholic fatty liver disease
DKK3
dickkopf-3
HFD
high fat diet
ASK1
apoptosis signal-regulating kinase 1
JNK
c-Jun N-terminal kinases
MAPK
mitogen-activated protein kinase
NC
normal chow
FBG
fasting blood glucose
FINS
fasting serum insulin
GTTs
glucose tolerance test
ITTs
insulin tolerance tests
TAG
triacylglyceride
TC
total cholesterol
NEFA
non-esterified fatty acid
H&E
haematoxylin and eosin
ALT
alanine amino transferase
AST
aspartate amino transferase, ALP, alkaline phosphatase
DMEM
Dulbecco’s modified Eagle’s medium
FBS
fetal bovine serum
ANOVA
analysis of variance
WAT
white adipose tissue
NTg
non-transgenic
LW/BW
ratio of liver weight to body weight
Dickkopf-3
Hepatic steatosis
Insulin resistance
Inflammation
ASK1
Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis
期刊论文
Journal of Hepatology, 2016, 卷号: 64, 期号: 6, 页码: 1365-1377
作者:
Xiang, Mei
;
Wang, Pi-Xiao
;
Wang, Ai-Bing
;
Zhang, Xiao-Jing
;
Zhang, Yaxing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/23
TRAF1
Tumor necrosis factor receptor-associated factor 1
NAFLD
non-alcoholic fatty liver disease
HFD
high fat diet
KO
knockout
LTG
liver-specific TRAF1 transgenic
NTG
non-transgenic
TNFR
Tumor necrosis factor receptor
GTT
glucose tolerance test
ITT
insulin tolerance test
AUC
areas under the curve
TG
triglyceride
TC
total cholesterol
NEFA
non-esterified fatty acid
HOMA-IR
homeostasis model assessment of the IR index
ALT
alanine amino transferase
AST
aspartate amino transferase
ANOVA
analysis of variance
LW/BW
liver weight/body weight
TRAF1
Hepatic steatosis
Inflammation
Insulin resistance
ASK1
Hepatic Transmembrane 6 Superfamily Member 2 Regulates Cholesterol Metabolism in Mice
期刊论文
Gastroenterology, 2016, 卷号: 150, 期号: 5, 页码: 1208-1218
作者:
Fan, Yanbo
;
Lu, Haocheng
;
Guo, Yanhong
;
Zhu, Tianqing
;
Garcia-Barrio, Minerva T.
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Translational Research
Gene Regulation
Lipid Disorder
Membrane Proteins
ABCG5
adenosine triphosphate–binding cassette, subfamily G, member 5
Alb
albumin
BW
body weight
CVD
cardiovascular disease
Cyp2C54
cytochrome P450, family 2, subfamily c, polypeptide 54
ER
endoplasmic reticulum
HDL
high-density lipoprotein
HFD
high-fat diet
KO
knockout
LDL-c
low-density lipoprotein cholesterol
LW
liver weight
MCP-1
monocyte chemoattractant protein-1
mRNA
messenger RNA
NASH
nonalcoholic steatohepatitis
PCR
polymerase chain reaction
TC
total cholesterol
TG
triglyceride
TM6SF2
transmembrane 6 superfamily member 2
TNF
tumor necrosis factor
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