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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
收藏
  |  
浏览/下载:237/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Ameliorative effect of morin, a plant flavonoid against Freund's complete adjuvant-induced polyarthritis in rats
期刊论文
PHARMACOGNOSY MAGAZINE, 2019, 卷号: 15, 期号: 60
作者:
Zhang, Guozhi
;
Kandhare, Amit D.
;
Mukherjee, Anwesha A.
;
Bodhankar, Subhash L.
;
Yin, Hailei
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/04
Arthritis
Freund's complete adjuvant
heme oxygenase-1
interleukin-1
interleukin-6
morin
nuclear factor erythroid 2-related factor-2
transforming growth factor-beta
tumor necrosis factor-alpha
Elevated serum soluble interleukin-2 receptor levels increase malignancy-related risk in patients on chronic hemodialysis
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2019, 卷号: 24, 期号: 9
作者:
Chen XiaoHong
;
Shen Bo
;
Xiang FangFang
;
Guo Man
;
Zou JianZhou
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Soluble interleukin-2 receptor
Hemodialysis
Malignancy event
Malignancy-related mortality
The effects of N-acetylcysteine on the Th1/Th2 ratio in elderly patients with chronic obstructive pulmonary disease
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 5
作者:
Wang, Jing
;
Jin, Quan
;
Hu, Zhixiong
;
Zhou, Haiying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
Interferon gamma
interleukin 4
acute exacerbation
Th1/Th2 ratio
COPD
N-acetylcysteine
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study.
期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:
Rebhun John F
;
Du Qin
;
Hood Molly
;
Guo Hailing
;
Glynn Kelly M
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Anti-inflammatory
BMD, bone mineral density
BSA, bovine serum albumin
Bmp4, bone morphogenic protein 4
CRE, cyclic adenosine monophosphate response element
CREB, cyclic adenosine monophosphate response element binding protein
DEXA, dual-energy X-ray absorptiometry
DMSO, Dimethyl sulfoxide
Drynaria fortunei
E2, estradiol
ER, estrogen receptor
ERE, estrogen response element
Epimedium brevicornu
Estrogenic
FBS, fetal bovine serum
Fsk, forskolin
Hprt, hypoxanthine-guanine phosphoribosyl-transferase
IL-1, interleukin 1
LBD, ligand binding domain
LBM, low bone mass
M-CSF, macrophage colony-stimulating factor
MAPK, mitogen activated protein kinase
NF-κβ, nuclear factor kappa beta
OP, osteoporosis
Osteoporosis
PTH, parathyroid hormone
PTHrp, PTH related peptide
RANKL, receptor activator of nuclear factor kappa beta ligand
RLU, relative luminescence unit
ROI, region of interest
Runx2, runt-related transcription factor 2
SFM, serum free media
TCM, traditional Chinese medicine
TNFα, tumor necrosis factor alpha
TRAP, tartrate-resistant acid phosphatase
UAS, upstream activating sequence
cAMP, cyclic adenosine monophosphate
qPCR, quantitative polymerase chain reaction
Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of Pain Induced by BmK-I
期刊论文
Neuroscience bulletin, 2019
作者:
Zhou Jingjing[1]
;
Zhang Xiaoxue[2]
;
Zhou You[3]
;
Wu Bin[4]
;
Tan Zhi-Yong[5]
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/04/22
BmK I
Brilliant Blue G
Interleukin 1β
Microglia
P2X7 receptor
Spinal dorsal horn
Hepatitis B virus X protein-induced SH2 domain-containing 5 (SH2D5) expression promotes hepatoma cell growth via an SH2D5-transketolase interaction
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 13
作者:
Zheng, Yongfa
;
Ming, Pingpo
;
Zhu, Chengliang
;
Si, Yu
;
Xu, Shilei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
hepatitis B virus (HBV
Hep B)
cancer biology
cell migration
interleukin 6 (IL-6)
inflammation
HBV X protein
HBV-associated HCC
IL-6-STAT3 signaling
SH2D5
transketolase
alpha-galactosylceramide generates lung regulatory cells through the activated natural killer T cells in mice
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 2
作者:
Chen, Qianhui
;
Guo, Xuxue
;
Deng, Nishan
;
Liu, Linlin
;
Chen, Shuo
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
alpha-galactosylceramide
interleukin-2
invariant natural killer cells
regulatory T cells
Soluble regulators of Interleukin-1 signaling: Novel biomarkers for early acute myocardial infarction diagnosis and to predict ischemia/reperfusion injury?
其他
2019-01-01
作者:
Wang, Menglong
;
Wan, Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Interleukin-1
Inflammation
Biomarker
IL-1Ra
sIL-1R2
MiR-146a promotes oligodendrocyte progenitor cell differentiation and enhances remyelination in a model of experimental autoimmune encephalomyelitis.
期刊论文
Neurobiology of disease, 2019, 卷号: Vol.125, 页码: 154-162
作者:
Jing Zhang
;
Zheng Gang Zhang
;
Mei Lu
;
Yi Zhang
;
Xia Shang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/17
Experimental
autoimmune
encephalomyelitis
Interleukin-1
receptor-associated
kinase
1
Oligodendrocyte
progenitor
cells
Oligodendrocytes
Remyelination
Toll-like
receptor
2
miR-146a
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