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PEGylated zinc oxide nanoparticles induce apoptosis in pancreatic cancer cells through reactive oxygen species 期刊论文
IET NANOBIOTECHNOLOGY, 2019, 卷号: 13, 期号: 5
作者:  Du, Yiqun;  Zhang, Jian;  Yan, Shiyan;  Tao, Zhonghua;  Wang, Chenchen
收藏  |  浏览/下载：45/0  |  提交时间：2019/12/05
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response 期刊论文
NATURE, 2018, 卷号: 560, 期号: 7718
作者:  Chen, Gang;  Huang, Alexander C.;  Zhang, Wei;  Zhang, Gao;  Wu, Min
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05
Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimus against Melanoma 期刊论文
SCIENTIFIC REPORTS, 2017
Dai, Jie; Wu, Shan; Kong, Yan; Chi, Zhihong; Si, Lu; Sheng, Xinan; Cui, Chuanliang; Fang, Jing; Zhang, Jue; Guo, Jun
收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03
Inactivation of Ricin Toxin by Nanosecond Pulsed Electric Fields Including Evidences from Cell and Animal Toxicity 期刊论文
SCIENTIFIC REPORTS, 2016
Wei, Kai; Li, Wei; Gao, Shan; Ji, Bin; Zang, Yating; Su, Bo; Wang, Kaile; Yao, Maosheng; Zhang, Jue; Wang, Jinglin
收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03
Unique antitumor property of the Mg-Ca-Sr alloys with addition of Zn 期刊论文
SCIENTIFIC REPORTS, 2016
Wu, Yuanhao; He, Guanping; Zhang, Yu; Liu, Yang; Li, Mei; Wang, Xiaolan; Li, Nan; Li, Kang; Zheng, Guan; Zheng, Yufeng; Yin, Qingshui
收藏  |  浏览/下载：7/0  |  提交时间：2017/12/03
Determination of glutathione in apoptotic SMMC-7221 cells induced by xylitol selenite using capillary electrophoresis 期刊论文
Biotechnology Letters, 2016, 卷号: 38, 期号: 5, 页码: 761-766
作者:  Wu, Xue;  Cao, Yu;  Zhang, Jian;  Lei, Ming;  Deng, Xiaojie
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/23
Nanosecond pulsed electric fields as a novel drug free therapy for breast cancer: An in vivo study 期刊论文
cancer letters, 2014
Wu, Shan; Wang, Yu; Guo, Jinsong; Chen, Qunzhi; Zhang, Jue; Fang, Jing
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/10
Chiral phosphoramide-catalyzed enantioselective synthesis of 2,3'-diindolylarylmethanes from indol-2-yl carbinols and indoles 期刊论文
chemical communications, 2014, 卷号: 50, 期号: 62, 页码: 8605-8608
Qi, Shuai; Liu, Chao-You; Ding, Jin-Ying; Han,Fu-She
收藏  |  浏览/下载：14/0  |  提交时间：2015/03/30
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载：26/0  |  提交时间：2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
异紫堇二酮体内外抗肿瘤活性研究 期刊论文
中国药理学通报, 2013, 卷号: 29, 期号: 6, 页码: 832-836
作者:  卜令娜;  赵剑喜;  李文广;  柳军玺;  刘晔玮
收藏  |  浏览/下载：25/0  |  提交时间：2013/12/26

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