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Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
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  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
A Validated HPLC-MS/MS Assay for 14-O-[(4,6-Diaminopyrimidine-2-yl)thioacetyl] Mutilin in Biological Samples and Its Pharmacokinetic, Distribution and Excretion via Urine and Feces in Rats
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 4, 页码: 17
作者:
Shang, Ruofeng
;
Fu, Yunxing
;
Liu, Yu
;
Yi, Yunpeng
;
Liang, Jianping
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  |  
浏览/下载:70/0
  |  
提交时间:2019/11/10
DPTM
HPLC-MS
MS
pharmacokinetics
distribution
excretion
Determination of DP-VPA and its active metabolite, VPA, in human plasma, urine, and feces by UPLC-MS/MS: A clinical pharmacokinetics and excretion study
期刊论文
DRUG TESTING AND ANALYSIS, 2019, 卷号: 11, 期号: 7
作者:
Li, Yi
;
Zhan, Huizhong
;
Fan, Yaxin
;
Zhang, Jing
;
Cao, Guoying
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  |  
浏览/下载:33/0
  |  
提交时间:2019/12/05
DP-VPA
epilepsy
excretion
pharmacokinetics
UPLC-MS
MS
Copper Sulfide Facilitates Hepatobiliary Clearance of Gold Nanoparticles through the Copper-Transporting ATPase ATP7B
期刊论文
ACS NANO, 2019, 卷号: 13, 期号: 5
作者:
Sun, Jingwen
;
Chen, Yixin
;
Yan, Bingfang
;
Lu, Wei
;
Wang, Xiaodong
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  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
copper sulfide nanoparticle
gold nanoparticle
hepatobiliary excretion
ATP7B
nanoconjugate
Effects of Absence of Constitutive Androstane Receptor on Bile Acid Homeostasis in Male and Female Mice.
期刊论文
Toxicological Sciences, 2019, 卷号: Vol.171 No.1, 页码: 132-145
作者:
Lickteig, Andrew J
;
Zhang, Youcai
;
Klaassen, Curtis D
;
Csanaky, Ivá
;
n L
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  |  
浏览/下载:12/0
  |  
提交时间:2019/11/21
bile acids
biliary excretion
constitutive androstane receptor
muricholic acid
taurocholic acid
Ultrasmall Quantum Dots with Broad-Spectrum Metal Doping Ability for Trimodal Molecular Imaging
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2019, 卷号: 29, 期号: 26
作者:
Tian, Rui
;
Shen, Zheyu
;
Zhou, Zijian
;
Munasinghe, Jeeva
;
Zhang, Xue
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  |  
浏览/下载:68/0
  |  
提交时间:2019/12/05
broad-spectrum metal doping
PET imaging
renal-excretion probes
trimodal molecular imaging
ultrasmall quantum dots
Determination of DP-VPA and its active metabolite, VPA, in human plasma, urine, and feces by UPLC-MS/MS: a clinical pharmacokinetics and excretion study.
期刊论文
Drug testing and analysis, 2019
作者:
Yi Li
;
Huizhong Zhan
;
Yaxin Fan
;
Jing Zhang
;
Guoying Cao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/17
DP-VPA
UPLC-MS/MS
epilepsy
excretion
pharmacokinetics
valproic acid
Comparative study of dechlorane plus (DP) in adult chickens and developing embryos: Stereo-selective bioaccumulation of DP in chickens.
期刊论文
Environmental pollution (Barking, Essex : 1987), 2019, 卷号: 247, 页码: 550-555
作者:
Li, Zong-Rui
;
Luo, Xiao-Jun*
;
Luo, Yuan -Lai
;
Zeng, Yan-Hong
;
Mai, Bi-Xian
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/24
Bioaccumulation
Chicken
Dechlorane plus
Excretion
Metabolism
Lipoprotein-associated phospholipase A2 is a risk factor for diabetic kidney disease
期刊论文
DIABETES RESEARCH AND CLINICAL PRACTICE, 2019, 卷号: 150, 页码: 194-201
作者:
Hu, Yun[1]
;
Li, Ting-ting[2]
;
Zhou, Wei[3]
;
Lu, Ting-ting[4]
;
Li, Feng-fei[5]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/24
Diabetic kidney disease
Lipoprotein-associated phospholipase A2
Type 2 diabetes
Albumin excretion rate
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