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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
收藏
  |  
浏览/下载:232/0
  |  
提交时间:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
Targeting KRAS mutant cancers: from druggable therapy to drug resistance
期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:
Zhu, Chunxiao
;
Guan, Xiaoqing
;
Zhang, Xinuo
;
Luan, Xin
;
Song, Zhengbo
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/23
KRAS mutations
Druggable
Resistance
Combination therapy
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119
作者:
Zhang, Pengge
;
Zhou, Zhixuan
;
Long, Wen
;
Yan, Yuping
;
Li, Youshan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
self-assembly
supramolecular coordination complex
combination chemotherapy
targeted cancer therapy
drug delivery
If small molecules immunotherapy comes, can the prime be far behind?
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218
作者:
Zhang, Jingyu
;
Zhang, Yu
;
Qu, Bingxue
;
Yang, Haiyan
;
Hu, Shengquan
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/06/15
Cancer immunotherapy
Small molecule inhibitors
Combination therapy
Tumor microenvironment
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:
Gao, Feng
;
Chen, Xiaoxu
;
Lu, Junyan
;
Hu, Shulei
;
Xu, Hui
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
Ceramide analogs
AKT inhibitor
MK2206
Colon cancer
Combination therapy
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
Tumor Exosomes Reprogrammed by Low pH Are Efficient Targeting Vehicles for Smart Drug Delivery and Personalized Therapy against their Homologous Tumor
期刊论文
ADVANCED SCIENCE, 2021, 页码: 13
作者:
Gong, Changguo
;
Zhang, Xiao
;
Shi, Min
;
Li, Feng
;
Wang, Shuang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/08/31
combination therapy
lipids rearrangement
low pH reprogramming
patient‐
derived xenografts
tumor exosomes
Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261
作者:
Zhao, Pengfei
;
Zhang, Jiaxin
;
Wu, Aihua
;
Zhang, Meng
;
Zhao, Yuge
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2021/05/24
Brain targeting delivery
Tumor-associated macrophage
Osimertinib resistance
Brain metastasis
Innate immunity
Combination therapy
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020)
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:
Wu, Jingwei
;
Zhang, Huan
;
Zhao, Guilong
;
Wang, Runling
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/08/17
SHP2 inhibitor
PTPN11 gene
allosteric
cancer
combination therapy
clinical trial
Remarkable Response of Toripalimab Combined with Chemotherapy in Sarcomatoid Carcinoma of Palatine Tonsil: A Case Report
期刊论文
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE, 2021, 卷号: 14
作者:
Huang, Jiahuan
;
Lei, Lei
;
Chen, Bo
;
Pan, Guoqiang
;
Wang, Xiaojiao
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/04/26
chemotherapy
combination therapy
palatine tonsil cancer
PD-1 inhibitor
sarcomatoid carcinoma
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