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昆明动物研究所 [45]
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浏览/检索结果:
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In Silico Identification of Novel Aromatic Compounds as Potential HIV-1 Entry Inhibitors Mimicking Cellular Receptor CD4
期刊论文
VIRUSES-BASEL, 2019, 卷号: 11, 期号: 8
作者:
Kornoushenko, Yuri V.
;
Tuzikov, Alexander V.
;
Jiang, Shibo
;
Andrianov, Alexander M.
;
Nikolaev, Grigory I.
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
HIV-1 gp120 protein
cellular receptor CD4
CD4-mimetics
virtual screening
in silico click chemistry
molecular docking
quantum chemical calculations
molecular dynamics simulations
binding free energy calculations
anti-HIV-1 drugs
Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176
作者:
Jin, KaiJun
;
Sang, YaLi
;
Han, Sheng
;
De Clercq, Erik
;
Pannecouque, Christophe
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Anti-HIV-1 activity
Dihydroquinazolines
DAPYs
Reverse transcriptase
Efavirenz
Etravirine
Antifungal Proteins with Antiproliferative Activity on Cancer Cells and HIV-1 Enzyme Inhibitory Activity from Medicinal Plants and Medicinal Fungi
期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2019, 卷号: 20, 页码: 265-276
作者:
Wong, Jack Ho
;
Ng, Tzi Bun
;
Wang, Hexiang
;
Cheung, Randy Chi Fai
;
Ng, Charlene Cheuk Wing
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/11/21
Antifungal proteins
anticancer
medicinal fungi
anti-HIV-1 enzymes
medicinal plants
Penicillixanthone A, a marine-derived dual-coreceptor antagonist as anti-HIV-1 agent
期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 10, 页码: 1467, 1471
作者:
Liu, Juan
;
Yang, Bin
;
Tan, Suiyi
;
Zhou, Xuefeng
;
Liu, Yonghong
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/09/09
Penicillixanthone A
anti-HIV-1
CCR5
CXCR4
marine fungi
硒唑合成的新方法研究及其应用
学位论文
北京: 中国科学院生态环境研究中心, 2018
作者:
乔俊飞
收藏
  |  
浏览/下载:141/0
  |  
提交时间:2019/07/16
硒唑,硒唑呋喃,利托那韦,抗肿瘤,抗hiv-1 Selenazole, Selenazofurin, Ritonaivr, Anti-cancer, Anti-hiv-1
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 8, 页码: 1348-1351
作者:
Huang, Boshi
;
Liu, Xinhao
;
Tian, Ye
;
Kang, Dongwei
;
Zhou, Zhongxia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
HIV-1 NNRTI
RDEA427
Carbonate prodrug
Anti-HIV activity
Metabolic
stability
Synthesis and biological evaluation of water-soluble derivatives of chiral gossypol as HIV fusion inhibitors targeting gp41
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 1
作者:
Yang, Jian
;
Li, Long-Long
;
Li, Ju-Rong
;
Yang, Jing-Xiang
;
Zhang, Fang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Chiral gossypol derivative
Amino acid derivative
D-Glucosamine derivative
Oligopeptide derivative
Taurine derivative
Anti-HIV-1
Gp41
Synthesis and Anti-HIV-1 Activity of Stapled HIV-1 Fusion Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: Vol.38 No.5, 页码: 1267-1270
作者:
Guo Ye
;
Fu Lili
;
Fan Xiaowen
;
Shi Xuanling
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
sifuvirtide
HIV-1
fusion
inhibitor
hydrocarbon
stapling
anti-HIV-1
activity
Novel tetrahydrofuran derivatives from Trigonostemon howii with their potential anti-HIV-1 activities
期刊论文
Bioorganic Chemistry, 2018, 期号: 79, 页码: 111–114
作者:
Xing-Yang Feng
;
Wan-Hui Zhao
;
Yan-Ping Liu
;
Yong-Tang Zheng
;
Zhi-Guo Sun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/09/25
Trigonostemon Howii
Tetrahydrofuran Derivatives
Trigonohowine
Anti-hiv-1 Activities
Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2017, 卷号: 14, 期号: 6
作者:
Wang, Rong
;
Xu, Aizhang
;
Zhang, Xueying
;
Wu, Jie
;
Freywald, Andrew
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
anti-CD40 Ab
CD40L signaling
chronic infection
CTL exhaustion
HIV Gag
mTORC1 pathway
T-cell anergy
therapeutic T-cell vaccine
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