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浏览/检索结果:
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Learning from low-rank multimodal representations for predicting disease-drug associations
期刊论文
BMC MEDICAL INFORMATICS AND DECISION MAKING, 2021, 卷号: 21, 期号: SUPPL1, 页码: 1-12
作者:
Hu, PW (Hu, Pengwei) [1]
;
Huang, YA (Huang, Yu-An) [2]
;
Mei, J (Mei, Jing) [3]
;
Leung, H (Leung, Henry) [4]
;
Chen, ZH (Chen, Zhan-Heng) [1]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/03/24
Disease-drug associations predictionLow-rank tensorsMultimodal fusion
GCNCDA: A new method for predicting circRNA-disease associations based on Graph Convolutional Network Algorithm
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-19
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, YM (Li, Yang-Ming)[ 3 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
;
Huang, YA (Huang, Yu-An)[ 5 ]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/06
iCDA-CGR: Identification of circRNA-disease associations based on Chaos Game Representation
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-22
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, JQ (Li, Jian-Qiang)[ 3 ]
;
Wang, L (Wang, Lei)[ 2,4 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 2 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/06
SAEROF: an ensemble approach for large-scale drug-disease association prediction by incorporating rotation forest and sparse autoencoder deep neural network
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 1-11
作者:
Jiang, HJ (Jiang, Han-Jing)[ 1,2,3 ]
;
Huang, YA (Huang, Yu-An)[ 4 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
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  |  
浏览/下载:37/0
  |  
提交时间:2020/12/11
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
收藏
  |  
浏览/下载:137/0
  |  
提交时间:2019/06/28
Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis
期刊论文
Cell, 2019, 卷号: 176, 页码: 1113-1127.e16
作者:
Yin Chengqian[1]
;
Zhu Bo[2]
;
Zhang Ting[3]
;
Liu Tongzheng[4]
;
Chen Shuyang[5]
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/04/22
NRAS
RAS
STK19
cancer
drug screening
kinase inhibitor
melanoma
melanomagenesis
targeted cancer therapy
Identification of potential plasma biomarkers and metabolic dysfunction for unstable angina pectoris and its complication based on global metabolomics
期刊论文
Bioscience reports, 2019, 卷号: 39
作者:
Wang Juan[1]
;
Xu Wenjuan[2]
;
Zhao Huihui[3]
;
Chen Jianxin[4]
;
Zhu Bin[5]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/04/22
Metabolomics
diagnostic biomarker
tryptophan metabolism
unstable angina pectoris
unstable angina pectoris complicated with diabetes mellitus
Identification of the copy number variant biomarkers for breast cancer subtypes
期刊论文
MOLECULAR GENETICS AND GENOMICS, 2019, 卷号: 294, 页码: 95-110
作者:
Pan, Xiaoyong[1]
;
Hu, XiaoHua[2]
;
Zhang, Yu-Hang[3]
;
Chen, Lei[4]
;
Zhu, LiuCun[5]
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/04/22
Breast cancer
Copy number variant
Monte Carlo feature selection
Dagging
Quantitative distinctive rule
CircRNAFisher: a systematic computational approach for de novo circular RNA identification
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 页码: 55-63
作者:
Jia, Guo-yi[1]
;
Wang, Duo-lin[2]
;
Xue, Meng-zhu[3]
;
Liu, Yu-wei[4]
;
Pei, Yu-chen[5]
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/04/22
circRNA
RNA-Seq
alternative splicing
pipeline
Ghrelin exhibited antidepressant and anxiolytic effect via the p38-MAPK signaling pathway in hippocampus
期刊论文
Progress in neuro-psychopharmacology & biological psychiatry, 2019, 卷号: 93, 页码: 11-20
作者:
Han Qiu-Qin[1]
;
Huang Hui-Jie[2]
;
Wang Ya-Lin[3]
;
Yang Liu[4]
;
Pilot Adam[5]
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/04/22
Chronic social defeat stress (CSDS)
Depression
Ghrelin
P38
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