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科研机构
山东大学 [8]
内容类型
期刊论文 [8]
发表日期
2018 [1]
2017 [2]
2016 [1]
2015 [3]
2014 [1]
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Metabolism of Piperaquine to Its Antiplasmodial Metabolites and Their Pharmacokinetic Profiles in Healthy Volunteers
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 卷号: 62, 期号: 8
作者:
Liu, Huixiang
;
Zhou, Hongchang
;
Cai, Tianyu
;
Yang, Aijuan
;
Zang, Meitong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
piperaquine
metabolite
antiplasmodial activity
healthy subjects
pharmacokinetics
Simultaneous determination of piperaquine and its N-oxidated metabolite in rat plasma using LC-MS/MS
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2017, 卷号: 31, 期号: 10
作者:
Liu, Huixiang
;
Zang, Meitong
;
Yang, Aijuan
;
Ji, Jianbo
;
Xing, Jie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
LC-ESI-MS
MS
metabolite
pharmacokinetics
piperaquine
rat plasma
The application of a novel high-resolution mass spectrometry-based analytical strategy to rapid metabolite profiling of a dual drug combination in humans
期刊论文
ANALYTICA CHIMICA ACTA, 2017, 卷号: 993, 页码: 38-46
作者:
Xing, Jie
;
Zang, Meitong
;
Liu, Huixiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/12
Combination drugs
Metabolite identification
High-resolution mass
spectrometry
Background subtraction
Mass defect filter
Ring double
bond filter
Metabolite identification of the antimalarial piperaquine in vivo using liquid chromatography-high-resolution mass spectrometry in combination with multiple data-mining tools in tandem
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2016, 卷号: 30, 期号: 8, 页码: 1324-1330
作者:
Yang, Aijuan
;
Zang, Meitong
;
Liu, Huixiang
;
Fan, Peihong
;
Xing, Jie
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
piperaquine
metabolites
liquid chromatography tandem high-resolution
mass spectrometry
mass defect filter
isotope pattern filter
Effect of CAR polymorphism on the pharmacokinetics of artemisinin in healthy Chinese subjects
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2015, 卷号: 30, 期号: 1, 页码: 123-126
作者:
Zang, Meitong
;
Zhao, Lixia
;
Zhu, Fanping
;
Li, Xinxiu
;
Yang, Aijuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
Artemisinin
Pharmacokinetics
Interindividual variability
Genotype
CAR
The application of high-resolution mass spectrometry-based data-mining tools in tandem to metabolite profiling of a triple drug combination in humans
期刊论文
ANALYTICA CHIMICA ACTA, 2015, 卷号: 897, 页码: 34-44
作者:
Xing, Jie
;
Zang, Meitong
;
Zhang, Haiying
;
Zhu, Mingshe
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
Combination drugs
Metabolite identification
High resolution mass
spectrometry
Background subtraction
Mass defect filter
Rapid Determination of Oligopeptides and Amino Acids in Soybean Protein Hydrolysates using High-Resolution Mass Spectrometry
期刊论文
PHYTOCHEMICAL ANALYSIS, 2015, 卷号: 26, 期号: 1, 页码: 15-22
作者:
Li, Xinxiu
;
Fan, Peihong
;
Zang, Meitong
;
Xing, Jie
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
High-resolution mass spectrometry
amino acids
oligopeptides
soybean
protein hydrolysates
Auto-induction of phase I and phase II metabolism of artemisinin in healthy Chinese subjects after oral administration of a new artemisinin-piperaquine fixed combination
期刊论文
MALARIA JOURNAL, 2014, 卷号: 13
作者:
Zang, Meitong
;
Zhu, Fanping
;
Li, Xinxiu
;
Yang, Aijuan
;
Xing, Jie
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
Artemisinin
Auto-induction metabolism
Healthy Chinese
CYP activity
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