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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
An Efficient Computational Model for Large-Scale Prediction of Protein-Protein Interactions Based on Accurate and Scalable Graph Embedding
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 2, 页码: 1-10
作者:
Su, XR (Su, Xiao-Rui)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Hu, L (Hu, Lun)[ 1,2,3 ]
;
Huang, YA (Huang, Yu-An)[ 1 ]
;
Wang, Y (Wang, Yi)[ 1,2,3 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
large-scale
protein-protein interaction
GraphZoom
weighted graph
graph embedding
In silico drug repositioning using deep learning and comprehensive similarity measures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 增刊3, 页码: 1-14
作者:
Yi, HC (Yi, Hai-Cheng) 1 , 2
;
You, ZH (You, Zhu-Hong) 1
;
Wang, L (Wang, Lei) 1
;
Su, XR (Su, Xiao-Rui) 1 , 2
;
Zhou, X (Zhou, Xi) 1
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/07/14
Drug repositioningDrug-disease interactionGated recurrent unitsGaussian interaction profile kernelMachine learning
Antioxidant Activity and the Potential Mechanism of the Fruit From Ailanthus altissima Swingle
期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 8, 期号: 12, 页码: 1-14
作者:
Mo, YN (Mo, Ya-nan) [1]
;
Cheng, F (Cheng, Feng) [1] , [2]
;
Yang, Z (Yang, Zhen) [1]
;
Shang, XF (Shang, Xiao-fei) [1]
;
Liang, JP (Liang, Jian-ping) [1]
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/03/24
Ailanthus altissima Swingle
antioxidant activityRAW264
7 cell
network pharmacology
invitro
antioxidant mechanism
A High Efficient Biological Language Model for Predicting Protein-Protein Interactions
期刊论文
CELLS, 2019, 卷号: 8, 期号: 2, 页码: 1-12
作者:
Wang, YB (Wang, Yanbin)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Yang, S (Yang, Shan)[ 1,2 ]
;
Li, X (Li, Xiao)[ 1 ]
;
Jiang, TH (Jiang, Tong-Hai)[ 1 ]
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  |  
浏览/下载:118/0
  |  
提交时间:2019/05/16
protein-protein interactions
bio-language processing
sentencepiece
convolution neural network
unigram language model
Size distribution of Platanus acerifolia allergen 3 (Pla a3) in Shanghai ambient size-resolved particles and its allergenic effects
期刊论文
ATMOSPHERIC ENVIRONMENT, 2019, 卷号: 198, 页码: 324-334
作者:
Zhou, Shumin[1]
;
Zhao, Hui[2]
;
Peng, Jiaxian[3]
;
Hong, Qiang[4]
;
Xiao, Kai[5]
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/04/22
Platanus acerifolia allergen 3 protein
Size-resolved ambient particles
Major inorganic ions
Allergenic effects
Pollen bursting
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 52
作者:
Dai Zi-Ru[1]
;
Ning Jing[2]
;
Sun Gui-Bo[3]
;
Wang Ping[4]
;
Zhang Feng[5]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/22
bufotalin
cytochrome P450 3A (CYP3A)
docking simulations
human liver microsomes (HLMs)
hydroxylation
Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis
期刊论文
Current pharmaceutical design, 2019
作者:
Lan Hai-Yue[1]
;
Zhao Bin[2]
;
Shen Yu-Li[3]
;
Li Xiao-Qin[4]
;
Wang Su-Juan[5]
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/04/22
Momordica cochinchinensis
clinical application
pharmacological activities
phytochemistry
toxicity
CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 224
作者:
Sun Meng-Yao[1]
;
Wang Su-Juan[2]
;
Li Xiao-Qin[3]
;
Shen Yu-Li[4]
;
Lu Jian-Rao[5]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/04/22
CXCL6
diabetics
fibrosis
kidney
pathway
Anodic Voltage Dependence of Ti-6Al-4V Substrates and Hydroxyapatite Coating
期刊论文
Journal of nanoscience and nanotechnology, 2019, 卷号: 19, 页码: 5700-5706
作者:
He Dai-Hua[1]
;
Wang Pu[2]
;
Liu Ping[3]
;
Liu Xin-Kuan[4]
;
Chen Xiao-Hong[5]
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/04/22
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