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CORC

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Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
收藏  |  浏览/下载：19/0  |  提交时间：2020/05/21
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Tingting Lu;  Jian Ge;  Tao Ren;  Wenchao Wang;  Junjie Wang
收藏  |  浏览/下载：36/0  |  提交时间：2019/04/24
Can Melatonin Improve the Osteopenia of Perimenopausal and Postmenopausal Women? A Meta-Analysis. 期刊论文
International journal of endocrinology, 2019, 卷号: 2019, 页码: 5151678
作者:  Bao, Tingting;  Zeng, Liuting;  Yang, Kailin;  Li, Yuehua*;  Ren, Fengying
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/27
Simulation study on AlGaN/GaN diode with Gamma-shaped anode for ultra-low turn-on voltage 期刊论文
SUPERLATTICES AND MICROSTRUCTURES, 2018
作者:  Wang, Zeheng;  Ren, Kailin;  Guo, Songnan;  Luo, Yi;  Jin, Xiaosheng(金晓盛)
收藏  |  浏览/下载：31/0  |  提交时间：2019/03/27
Structural characterizations of protonated homodimers of amino acids:Revealed by infrared multiple photon dissociation spectroscopy and theoretical calculations 期刊论文
Chinese Chemical Letters, 2018, 卷号: 第9期, 页码: 1333-1339
作者:  Lifu Ma;  Juan Ren;  Ruxia Feng;  Kailin Zhang;  Xianglei Kong
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/26
The consensus on the monitoring, treatment, and prevention of leukemia relapse after allogeneic hematopoietic stem cell transplantation in China 期刊论文
2018, 卷号: 438, 页码: 63-75
作者:  Wang, Yu;  Chen, Hu;  Chen, Jing;  Han, Mingzhe;  Hu, JianDa
收藏  |  浏览/下载：10/0  |  提交时间：2020/01/03
Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
作者:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping
收藏  |  浏览/下载：42/0  |  提交时间：2019/06/17
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557
作者:  Wang, Beilei;  Deng, Yuanxin;  Chen, Yongfei;  Yu, Kailin;  Wang, Aoli
收藏  |  浏览/下载：39/0  |  提交时间：2018/08/16
Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl) phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 131, 页码: 107-125
作者:  Liang, Qianmao;  Chen, Yongfei;  Yu, Kailin;  Chen, Cheng;  Zhang, Shouxiang
收藏  |  浏览/下载：37/0  |  提交时间：2018/07/26
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:  Wang, Aoli;  Li, Xixiang;  Wu, Hong;  Zou, Fengming;  Yan, Xiao-E
收藏  |  浏览/下载：34/0  |  提交时间：2018/07/26

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