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浏览/检索结果: 共14条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing 期刊论文 European Journal of Medicinal Chemistry, 2019, 卷号: 182 作者:  Zhao T.;  Meng Q.;  Kang D.;  Ji J.;  De Clercq E. 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Antiviral activity  Chemical space  Drug design  Indolylarylsulfones  Molecular modeling  NNRTIs  SAR   Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs 期刊论文 Bioorganic and medicinal chemistry, 2013, 卷号: 21, 期号: 23, 页码: 7398-7405 作者:  Rai,D.;  Chen,W.;  Tian,Y.;  Chen,X.;  Zhan,P. 收藏  |  浏览/下载：1/0  |  提交时间：2019/12/23 Anti-HIV activity  HIV-1  NNRTIs  Pyrimidine  Reverse transcriptase   Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs 期刊论文 Bioorganic and medicinal chemistry, 2013, 卷号: 21, 期号: 7, 页码: 2128-2134 作者:  Li,D.;  Zhan,P.;  Liu,H.;  Pannecouque,C.;  Balzarini,J. 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/23 AIDS  Anti-HIV-1 activity  HIV-1  NNRTIs  Pyridazine derivatives   Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors 期刊论文 Bioorganic and Medicinal Chemistry Letters, 2013, 卷号: 23, 期号: 24, 页码: 6593-6597 作者:  Chen,X.;  Liu,X.;  Meng,Q.;  Wang,D.;  Liu,H. 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/23 DAPY  Dual conformations  HIV-1 NNRTIs  Molecular hybridization  Piperidin-4-yl-aminopyrimidines   Design, synthesis and biological evaluation of N2,N 4-disubstituted-1,1,3-trioxo-2H,4H-pyrrolo[1,2-b][1,2,4,6] thiatriazine derivatives as HIV-1 NNRTIs 期刊论文 Bioorganic and medicinal chemistry, 2013, 卷号: 21, 期号: 22, 页码: 7091-7100 作者:  Chen,W.;  Zhan,P.;  DeClercq,E.;  Pannecouque,C.;  Balzarini,J. 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 Drug design  Heterocycle  HIV  NNRTIs  Pyrrolothiatriazine  Reverse transcriptase  Thienothiadiazine   Arylazolylthioacetanilide. Part 11: Design, synthesis and biological evaluation of 1,2,4-triazole thioacetanilide derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors 期刊论文 Medicinal chemistry, 2013, 卷号: 9, 期号: 7, 页码: 968-973 作者:  Li,Z.;  Cao,Y.;  Zhan,P.;  Pannecouque,C.;  Balzarini,J. 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 1  2  4-triazole thioacetanilides  AIDS  Anti-HIV-1 activity  HIV-1  NNRTIs   Synthesis, and in vitro enzymatic and antiviral evaluation of d4T polyphosphate derivatives as chain terminators 期刊论文 Chemistry and Biodiversity, 2012, 卷号: 9 作者:  Yang S., Pannecouque C., Herdewijn P. 收藏  |  浏览/下载：1/0  |  提交时间：2019/12/19 Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors 期刊论文 European Journal of Medicinal Chemistry: Chimie Therapeutique, 2012, 页码: 60-66 作者:  Chen,X.;  Zhan,P.;  Pannecouque,C.;  Balzarini,J.;  DeClercq,E. 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 AIDS  HIV-1  NNRTIs  Piperidine  SAR  Triazine   Synthesis, drug release and anti-HIV activity of a series of PEGylated zidovudine conjugates 期刊论文 International Journal of Biological Macromolecules: Structure, Function and Interactions, 2012, 卷号: 50, 期号: 4, 页码: 974-980 作者:  Li, W.;  Wu, J.;  Zhan, P.;  Chang, Y.;  Pannecouque, C. 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 Anti-HIV activity  PEGylation  Pharmacokinetics  Sustained release  Zidovudine   Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs 期刊论文 Bioorganic and Medicinal Chemistry Letters, 2012, 卷号: 22, 期号: 23, 页码: 7155-7162 作者:  Zhan,P.;  Li,X.;  Li,Z.;  Chen,X.;  Tian,Y. 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 1  2  4-Triazine  Anti-HIV-1 activity  Heterocycle  HIV reverse transcriptase  NNRTIs  SAR  Structure-based bioisosterism strategy  Synthesis