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大连理工大学 [11]
上海药物研究所 [11]
北京大学 [4]
中国科学院大学 [1]
华南理工大学 [1]
武汉大学 [1]
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期刊论文 [30]
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2021 [1]
2020 [2]
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2017 [4]
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2015 [3]
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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/08/17
Photochemical reaction of tricresyl phosphate (TCP) in aqueous solution: Influencing factors and photolysis products
期刊论文
Chemosphere, 2020, 卷号: 241, 页码: 124971
作者:
Sun, Shibin
;
Jiang, Jingqiu
;
Zhao, Hongxia
;
Wan, Huihui
;
Qu, Baocheng
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/02
Environmental factors,Kinetics,Photolysis products,Radical analysis,Tricresyl phosphate (TCP)
A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats
期刊论文
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10
作者:
Li, Xin
;
Wu, Ming
;
Chen, Limin
;
Lu, Junyan
;
Li, Guo
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
FTY720
Sphingosine-1-phosphate
Cordyceps sinensis
Autosomal dominant polycystic kidney disease
Inflammation
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483
作者:
Zhu, Kongkai
;
Jiang, Chengshi
;
Tao, Hongrui
;
Liu, Jingqiu
;
Zhang, Hua
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  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Resynthesis
Virtual screening
Molecular docking
Molecular dynamics simulation
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1751-1758
作者:
Song, Yakai
;
Li, Linjuan
;
Chen, Yantao
;
Liu, Jingqiu
;
Xiao, Senhao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
DOT1L
MLL-rearranged leukemia
AlphaLISA
HTS
Novel inhibitors
Measurement and prediction of bioconcentration factors of organophosphate flame retardants in common carp (Cyprinus carpio)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 166, 页码: 270-276
作者:
Bekele, Tadiyose Girma
;
Zhao, Hongxia
;
Wang, Yan
;
Jiang, Jingqiu
;
Tan, Feng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
Organophosphate flame retardants
Common carp
Bioconcentration
Tissue distribution
QSAR
Occurrence and profiles of halogenated phenols, polybrominated diphenyl ethers and hydroxylated polybrominated diphenyl ethers in the effluents of waste water treatment plants around Huang-Bo Sea, North China.
期刊论文
The Science of the total environment, 2018, 卷号: 622-623, 页码: 1-7
作者:
Jiang Jingqiu
;
Zhao Hongxia
;
Sun Shibin
;
Wang Yuntao
;
Liu Sisi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/02
Effluent,Halogenated phenols,OH-PBDEs,PBDEs,Waste water treatment plant
developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302
作者:
Zhu Maorong
;
Du Daohai
;
Hu Junchi
;
Li Lianchun
;
Liu Jingqiu
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
PRC2
EZH2
EED
protein-protein interaction
fluorescence polarization
high-throughput screening
apomorphine hydrochloride
oxyphenbutazone
nifedipine
ergonovine maleate
Photochemical reactions between bromophenols and hydroxyl radical generated in aqueous solution: A laser flash photolysis study
期刊论文
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 卷号: 336, 页码: 63-68
作者:
Jiang, Jingqiu
;
Zhao, Hongxia
;
Liu, Sisi
;
Chen, Xiuying
;
Jiang, Xiao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/02
Bromophenols
Hydroxyl radical
Photochemcial reaction
Laser flash photolysis
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