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科研机构
上海药物研究所 [8]
复旦大学上海医学院 [3]
内容类型
期刊论文 [11]
发表日期
2021 [1]
2018 [10]
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Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:
Gong, Grace Qun
;
Wang, Ke
;
Dai, Xin-Chuan
;
Zhou, Yan
;
Basnet, Rajesh
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:
Wang, Jia
;
Gong, Grace Qun
;
Zhou, Yan
;
Lee, Woo-Jeong
;
Buchanan, Christina Maree
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
high throughput screening
PI3 kinase
PI3K alpha H1047R
inhibitors
molecular modeling
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:
Basnet, Rajesh
;
Gong, Grace Qun
;
Li, Chenyao
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
SGK
AKT
PI3K
Cancer
Signalling: Kinase
Inhibitor
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11
作者:
Wang, Jia
;
Gong, Grace Qun
;
Zhou, Yan
;
Lee, Woo-Jeong
;
Buchanan, Christina Maree
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
high throughput screening
PI3 kinase
PI3K alpha H1047R
inhibitors
molecular modeling
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5
作者:
Basnet, Rajesh
;
Gong, Grace Qun
;
Li, Chenyao
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
SGK
AKT
PI3K
Cancer
Signalling: Kinase
Inhibitor
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12
作者:
Chen, Yi
;
Gong, Grace Qun
;
Wang, Ke
;
Dai, Xin-Chuan
;
Zhou, Yan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
serum and glucocorticoid-regulated kinase
SGK3
high-throughput screening
inhibitors
molecular modeling
highthroughputscreeningcampaignsagainstapi3kisoformbearingtheh1047rmutationidentifiedpotentialinhibitorswithnovelscaffolds
期刊论文
actapharmacologicasinica, 2018, 卷号: 039, 期号: 011, 页码: 1816
作者:
Wang Jia
;
Gong Grace Qun
;
Zhou Yan
;
Lee Woojeong
;
Buchanan Christina Maree
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
脚手架
屏蔽
识别
产量
运动
类脂化合物
混合物
新陈代谢
identificationstructuremodificationandcharacterizationofpotentialsmallmoleculesgk3inhibitorswithnovelscaffolds
期刊论文
中国药理学报英文版, 2018, 卷号: 039, 期号: 012, 页码: 1902
作者:
Grace Qun Gong
;
Ke Wang
;
XinChuan Dai
;
Yan Zhou
;
Rajesh Basnet
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
serum
and
glucocorticoid-regulated
kinase
SGK3
high-throughput
screening
inhibitors
molecular
modeling
serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention
期刊论文
actapharmaceuticasinicab, 2018, 卷号: 000, 期号: 005, 页码: 767
作者:
Basnet Rajesh
;
Gong Grace Qun
;
Li Chenyao
;
Wang Mingwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
SGK
AKT
PI3K
Cancer
Signalling
Kinase
Inhibitor
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