QQ客服 官方微博 反馈留言

浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong 收藏  |  浏览/下载：11/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文 CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2 作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan 收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01 Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文 CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56 作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Homologous recombination repair defects  Olaparib  Growth inhibition  Patient-derived xenografts  Pharmacokinetics   Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168 作者:  He, Jin-Xue;  Wang, Meng;  Huan, Xia-Juan;  Chen, Chuan-Huizi;  Song, Shan-Shan 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 MPH  PARP inhibitor  homologous recombination  antitumor activity  synthetic lethality   Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 7, 页码: 2885-2903 作者:  Ye, Na;  Chen, Chuan-Huizi;  Chen, TianTian;  Song, Zilan;  He, Jin-Xue 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08