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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
Diterpenoid alkaloids from Aconitum barbatum var. puberulum Ledeb
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 181, 期号: 1, 页码: 1-9
作者:
Ablajan, N (Ablajan, Nurfida)[ 1,2,4 ]
;
Zhao, B (Zhao, Bo)[ 1,2 ]
;
Zhao, JY (Zhao, Jiang-Yu)[ 1,2 ]
;
Wang, BL (Wang, Bian-Lin)[ 1,2 ]
;
Sagdullaev, SS (Sagdullaev, Sh Sh)[ 3 ]
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  |  
浏览/下载:47/0
  |  
提交时间:2021/01/26
Aconitum barbatum var. puberulum Ledeb.
Ranunculaceae
Diterpenoid alkaloids
Barpuberudine
Barpubesines
Barpubenines
Biological activities
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
Improving Distant Supervised Relation Extraction with Noise Detection Strategy
期刊论文
APPLIED SCIENCES-BASEL, 2021, 卷号: 11, 期号: 5, 页码: 1-14
作者:
Meng, XY (Meng, Xiaoyan)[ 1,2,3,4 ]
;
Jiang, TH (Jiang, Tonghai)[ 1,3 ]
;
Zhou, X (Zhou, Xi)[ 1,2,3 ]
;
Ma, B (Ma, Bo)[ 1,2,3 ]
;
Wang, Y (Wang, Yi)[ 1,2,3 ]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/05/06
relation extraction
distant supervision
noise detection
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
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  |  
浏览/下载:34/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
One-pot synthesis of unprotected PtPd nanoclusters with enhanced catalytic activity, durability, and methanol-tolerance for oxygen reduction reaction
期刊论文
APPLIED SURFACE SCIENCE, 2019, 卷号: 473, 期号: 4, 页码: 318-325
作者:
Liu, J (Liu, Jing)[ 1,2,4 ]
;
Yin, J (Yin, Jiao)[ 1,2 ]
;
Feng, B (Feng, Bo)[ 1,2 ]
;
Li, F (Li, Fan)[ 1,2 ]
;
Wang, F (Wang, Fu)[ 1,2,3 ]
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  |  
浏览/下载:88/0
  |  
提交时间:2019/02/25
Unprotected
PtPd nanoclusters
Ordered mesoporous carbon
Oxygen reduction reaction
One-step synthesis of novel phosphorus nitride dots for two-photon imaging in living cells
期刊论文
CHEMICAL COMMUNICATIONS, 2019, 卷号: 55, 期号: 32, 页码: 4719-4722
作者:
Wu, XX (Wu, Xiaoxia)[ 1,2 ]
;
Shu, J (Shu, Jie)[ 3 ]
;
Feng, B (Feng, Bo)[ 1 ]
;
Yang, LY (Yang, Lingyan)[ 2 ]
;
Lan, JZ (Lan, Jinze)[ 2 ]
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/06/28
Large elastocaloric effect driven by stress-induced two-step structural transformation in a directionally solidified Ni55Mn18Ga27 alloy
期刊论文
SCRIPTA MATERIALIA, 2019, 卷号: 163, 页码: 116-120
作者:
Li, Dong[1]
;
Li, Zongbin[2]
;
Yang, Jiajing[3]
;
Li, Zhenzhuang[4]
;
Yang, Bo[5]
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/04/22
Ni-Mn-Ga alloys
Elastocaloric effect
Stress-induced martensitic transformation
Inter-martensitic transformation
Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis
期刊论文
Cell, 2019, 卷号: 176, 页码: 1113-1127.e16
作者:
Yin Chengqian[1]
;
Zhu Bo[2]
;
Zhang Ting[3]
;
Liu Tongzheng[4]
;
Chen Shuyang[5]
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/04/22
NRAS
RAS
STK19
cancer
drug screening
kinase inhibitor
melanoma
melanomagenesis
targeted cancer therapy
Inhibition of UGT1A1 by natural and synthetic flavonoids
期刊论文
International journal of biological macromolecules, 2019, 卷号: 126, 页码: 653-661
作者:
Liu Xin-Yu[1]
;
Lv Xia[2]
;
Wang Ping[3]
;
Ai Chun-Zhi[4]
;
Zhou Qi-Hang[5]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/04/22
Flavonoids
Structure-inhibition relationships
UGT1A1
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