CORC

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CORC

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Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载：113/0  |  提交时间：2021/05/24
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:  Qiu, Yunguang;  Huang, Lu;  Fu, Jie;  Han, Chenxia;  Fang, Jing
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载：92/0  |  提交时间：2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
The non-coding RNA OTUB1-isoform2 promotes ovarian tumour progression and predicts poor prognosis 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 卷号: 22, 期号: 10
作者:  Wang, Shunni;  Ning, Yan;  Wei, Ping;  Cai, Dongliag;  Lu, Linghui
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05
Reversal of docetaxel resistance in prostate cancer by Notch signaling inhibition 期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: Vol.29 No.9, 页码: 871-879
作者:  Qiu, Shi;  Deng, Linghui;  Bao, Yige;  Jin, Kun;  Tu, Xiang
收藏  |  浏览/下载：4/0  |  提交时间：2019/02/28
Comparative efficacy and safety of phosphodiesterase-5 inhibitors with selective serotonin reuptake inhibitors in men with premature ejaculation: A systematic review and Bayesian network meta-analysis. 期刊论文
Medicine, 2018, 卷号: Vol.97 No.49, 页码: e13342
作者:  Jin Kun;  Deng Linghui;  Qiu Shi;  Tu Xiang;  Li Jiakun
收藏  |  浏览/下载：7/0  |  提交时间：2019/02/25
Comparative efficacy and safety of phosphodiesterase-5 inhibitors with selective serotonin reuptake inhibitors in men with premature ejaculation: A systematic review and Bayesian network meta-analysis. 期刊论文
Medicine, 2018, 卷号: Vol.97 No.49, 页码: e13342
作者:  Jin Kun;  Deng Linghui;  Qiu Shi;  Tu Xiang;  Li Jiakun
收藏  |  浏览/下载：9/0  |  提交时间：2019/02/25
Outcomes of bisphosphonate and its supplements for bone loss in kidney transplant recipients: a systematic review and network meta-analysis 期刊论文
BMC Nephrology, 2018, 卷号: Vol.19 No.1, 页码: 1-12
作者:  Yan Yang;  Shi Qiu;  Linghui Deng;  Xi Tang;  Xinrui Li
收藏  |  浏览/下载：2/0  |  提交时间：2019/02/28

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